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US 2009/0023639 A1Published application
Methods of Treatment
AssigneeImperial Innovations Limited
InventorsStefan Dietmar Anker, Andrew Justin Stewart Coats
Life of this patent
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AssigneeImperial Innovations Limited
InventorsStefan Dietmar Anker, Andrew Justin Stewart Coats
Estimating the term…
A method of treating weight loss due to underlying disease in a patient, the method comprising administering to the patient an effective amount of an agent which reduces sympathetic nervous system activity. A method of treating weight loss due to underlying disease in a patient the method comprising administering to the patient an effective amount of any one or more of the following: a compound which inhibits the effect of aldosterone such as an aldosterone antagonist; a chymase inhibitor; a cathepsin B inhibitor; a β receptor blocker; an imidazoline receptor antagonist; a centrally acting α receptor antagonist; a peripherally acting α receptor antagonist; a ganglion blocking agent; a drug that has an effect on cardiovascular reflexes and thereby reduces SNS activity such as an opiate; scopolamine; an endothelin receptor antagonist; and a xanthine oxidase inhibitor. The methods are particularly useful in treating cardiac cachexia.
A method of treating weight loss due to underlying disease in a patient, the method comprising administering to the patient an effective amount of an agent selected from the group consisting of an agent which reduces sympathetic nervous system activity and/or improves cardiovascular reflex status, a compound which inhibits the effect of aldosterone, a chymase inhibitor, a cathepsin inhibitor, a β receptor blocker, an imidazoline receptor antagonist, an imidazoline receptor antagonist, a peripherally acting α receptor antagonist, a ganglion blocking agent, a drug that has an effect on cardiovascular reflexes and thereby reduces SNS activity, an opiate, scopolamine, an endothelin receptor antagonist, a xanthine oxidase inhibitor, and erythropoietin.
A method of treating weight loss due to underlying disease in a patient the method comprising electrically stimulating the patient's muscles.
32-34. (canceled)
A method of treating or preventing weight loss due to the aging process in a patient the method comprising administering to the patient an effective amount of an agent which reduces sympathetic nervous system activity
A method of treating or preventing weight loss due to the aging process in a patient the method comprising administering to the patient an effective amount of a compound selected from the group consisting of a compound which inhibits the effect of aldosterone antagonist;
A method of treating or preventing weight loss due to the aging process in a patient the method comprising electrically stimulating the patient's muscles.
A method of enhancing exercise performance in a healthy patient the method comprising administering to the individual an effective amount of an agent which reduces sympathetic nervous system activity.
A method of enhancing exercise performance in a healthy individual the method comprising administering the individual an effective amount of a compound selected from the group consisting of a compound which inhibits the effect of aldosterone such as an aldosterone antagonist;
A method of enhancing exercise performance in a healthy patient the method comprising electrically stimulating the patient's muscles.
A method of preventing weight loss consequent to a cardiovascular disorder in a patient at risk of heart disease the method comprising administering to the patient an effective amount of a compound selected from the group consisting of a compound with an inhibiting effect on aldosterone;
42-43. (canceled)
Dependencies are inferred from the claim text.