Method and Device for Detection of Erythromycin-Induced Clindamycin Resistance
AssigneeSiemens Healthcare Diagnostics Inc.
InventorsKatherine S. Sei, Gerard D. Bordash, Collette Y. Wehr, Barbara L. Zimmer, Judith A. Johnston, Lou Ann Barnett
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Abstract
A device and method are provided for determination of erythromycin-induced clindamycin resistance. The device is preferably a test panel containing one or more wells each having a known concentration(s) of erythromycin and known concentration(s) of clindamycin. After inoculation of the wells with a sample and incubation, the wells are analyzed for growth and to determine whether sample contains a microorganism that expresses erythromycin-induced clindamycin resistance.
Claims16
A device for use in the determination of erythromycin-induced clindamycin resistance comprising:
- a panel having a first at least one well containing a growth medium, a known amount of erythromycin, and a known amount of clindamycin.
A method for the determination of erythromycin-induced clindamycin resistance comprising:
- providing a panel having at least one well containing a growth media, a known amount of erythromycin, and a known amount of clindamycin;
- inoculating said at least one well with a sample suspected of containing microorganisms;
- incubating said panel at conditions suitable for growth of the microorganisms in the wells;
- analyzing the at least one well for growth of the microorganisms;
- determining the presence or absence of erythromycin-induced clindamycin resistance based on the growth of microorganisms in said at least one well.
A method for the determination of erythromycin-induced clindamycin resistance comprising:
- providing a panel having a first at least one well containing a growth media, a known amount of erythromycin, and a known amount of clindamycin and a second at least one well containing a growth media and a known amount of clindamycin;
- inoculating said first at least one well and said second at least one well with a sample suspected of containing microorganisms;
- incubating said panel at conditions suitable for growth of the microorganisms in the wells;
- analyzing said first at least one well and said second at least one well for growth of the microorganisms;
- determining the presence or absence of erythromycin-induced clindamycin resistance based on the growth of microorganisms in said first at least one well and said second well.
Dependencies are inferred from the claim text.