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US 2009/0023172 A1Published application
GTP Cyclohydrolase II as a Target for Fungicides
AssigneeBASF SE
InventorsAnnette FREUND, Franz Rohl, Henning Althofer, Marvin Karos, Bruno Kaesler, Thierry Lacour
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Abstract
The present invention relates to the identification of fungal GTP cyclohydrolase II as a target for fungicides, to a method for identifying antifungal agents based on fungal GTP cyclohydrolase II, and also to the use of compounds identified as fungicides via the abovementioned method.
Claims4
1-21. (canceled)
A method for determination of GTP cyclohydrolase I or II activity comprising the steps of:
- a) adding GTP or GTP analog, NAD+ and formate dehydrogenase to a sample comprising GTP cyclohydrolase II or I;
- and
- b) determining the production of NADH of the sample.
Dependencies are inferred from the claim text.