Method For the in Vitro Diagnosis of Autoimmune Immune Response by Detection of Antibodies Directed Against The Pentraxin 3 Antigen
OwnerPascale Jeannin, Yves Delneste +1inventors
InventorsPascale Jeannin, Yves Delneste, Alberto Mantovani
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Abstract
A method for the in vitro diagnosis of an autoimmune immune response in an individual by detection, in a biological fluid from said individual, of antibodies directed against the pentraxin 3 (PTX3) antigen, characterized in that the presence of antibodies directed against the PTX3 antigen (anti-PTX3 antibodies) are determined in a biological fluid from the individual, and kits for implementing the method.
Claims35
A method for in vitro diagnosis of an autoimmune immune response in a subject by detection in a biological fluid of said subject of antibodies directed against the pentraxin 3 antigen (PTX3) wherein a presence of antibodies directed against the PTX3 antigen (anti-PTX3 antibodies) is determined in the serum of said subject and existence of an autoimmune immune response in the subject is concluded on this basis.
A diagnostic kit for detection and/or quantification in a biological fluid of antibodies directed against the PTX3 antigen comprising:
- a) a solid support, wherein the PTX3 antigen is fixed to the solid support.
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Dependencies are inferred from the claim text.