ESR1 and Cervical Cancer
AssigneeOncomethylome Sciences SA
InventorsAte Van Der Zee, Bea Wisman
Life of this patent
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Abstract
The present invention provides methods and kits for detecting susceptibility to, or the incidence of, cervical cancer in a sample comprising determining the methylation status of the ESR1 gene, optionally as part of a panel of genes. Also provided are methods and kits which involve determining the expression levels of genes including the ESR1 gene in order to diagnose cervical cancer.
Claims29
A method of detecting susceptibility to, or the incidence of, cervical cancer in a sample comprising determining the methylation status of ESR1.
A kit for use in detecting susceptibility to, or the incidence of, cervical cancer in a cervical sample from a patient comprising;
- a) gene specific primers for determining the methylation status of the ESR1 gene;
- and
- b) an Ayre's spatula and/or an endocervical brush for removing cervical cells from the patient.
Dependencies are inferred from the claim text.