Use of fructus schisandrae and extracts thereof in preventing and decreasing toxic and side effects of antineoplastic drugs
AssigneeZhe Jiang Dinghui Pharm Co. Ltd.
InventorXun Hu
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Abstract
Use of Fructus schisandrae in preparation of medicaments for preventing and reducing toxicity and side effects of antineoplastic agents. The toxicity and side effects of antineoplastic agents are cardiovascular toxicity, hepatotoxicity, nephrotoxicity, suppression of bone marrow, immunosuppression, or alopecia etc induced by antineoplastic agents. Fructus schisandrae and extracts thereof, especially ethanol extracts, schisandrin B, are effective in reducing antineoplastic agent's toxicity and side effects.
Claims20
A method for treating cancer in a mammal comprising administering to the subject in need thereof. Fructus schisandrae or the extract of Fructus schisandrae during or before administering an antineoplastic agent to the subject.
A method for preventing or reducing the toxicity and/or side effect of antineoplastic agent comprising administering to the subject in need thereof Fructus schisandrae or the extract of Fructus schisandrae.
A kit for treating cancer in a mammal comprising:
- a first composition comprising a pharmaceutically acceptable carrier and an antineoplastic agent, and
- a second composition comprising a pharmaceutically acceptable carrier and Fructus schisandrae or the extract of Fructus schisandrae.
A method of improving cardiac function comprising administering to the subject in need thereof of a composition which comprises (a) a pharmaceutically acceptable carrier and (b) Fructus schisandrae or the extract of Fructus schisandrae.
Use of Fructus schisandrae in the preparation of a medicament for improving cardiac function.
Dependencies are inferred from the claim text.