Back to results
US 2009/0022769 A1Published application
Medical Devices Comprising Polymeric Drug Delivery Systems With Drug Solubility Gradients
AssigneeMedtronic Vascular, Inc.
InventorsMingfei Chen, Peiwen Cheng, Kishore Udipi
Life of this patent
Estimating the term…
Abstract
Disclosed are drug delivery systems comprising drugs admixed with polymers having drug solubility gradients and methods of making the polymers. Also disclosed are medical devices having coatings thereon comprising the drug solubility gradient-containing polymers and at least one drug.
Claims26
A medical device comprising a controlled-release drug delivery system comprising:
- a drug admixed with a polymer, said polymer comprising a drug solubility gradient.
A vascular stent comprising a controlled-release drug delivery system comprising:
- a drug admixed with a polymer comprising a drug solubility gradient, said polymer comprising hexyl methacrylate and N-vinyl pyrrolidinone.
A method of preparing a drug solubility gradient comprising:
- preparing a first charge solution comprising at least one monomer under conditions that promote polymerization;
- preparing at least one additional charge solution comprising at least one monomer;
- adding said additional charge solution to said first charge solution;
- and
- reacting said first charge solution and said additional charge solution until the desired degree of polymerization has been reached.
2 more elements
Dependencies are inferred from the claim text.