Organic compounds
AssigneeGivaudan SA
InventorsGeorg Frater, Rita Cannas, Benjamin J. Costa, Jutta Hotz
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Abstract
The present invention refers to a process for the production of controlled-release aqueous compositions comprising an active ingredient releasably contained within polymeric particles. The polymeric particles are obtainable by ring-opening metathesis polymerisation of a monomer of the general formula (I) wherein R1 and R2 have the same meaning as given in the specification, or a mixture thereof, in an aqueous phase in the presence of a ruthenium catalyst, an emulsifier, and an active ingredient.
Claims7
An aqueous emulsion comprising polymer particles containing an active ingredient, wherein the polymer with a Tg between 15° C. and 150° C. is obtainable by ring-opening metathesis polymerisation of a monomer of the general formula (I)
- wherein
- R1 and R2 are independently methoxymethyl or —CO2Me;
- or
- R1 and R2 form together a divalent radical —C(O)N(CH3)C(O)—which forms together with the carbon atoms to which they are attached a 5-membered heterocyclic ring;
- and
- the bond between C2 and C3 is a single bond;
- or
- the bond between C2 and C3 together with the dotted line represents a double bond;
- or a mixture thereof,
- in an aqueous phase in the presence of a ruthenium catalyst, an emulsifier, and an active ingredient.
A method of preparing polymer particles comprising the steps of:
- a. admixing a monomer of the general genera formula (I) or a mixture thereof,
- wherein:
- R1 and R2 are independently methoxymethyl or —CO2Me;
- or
- R1 and R2 form together a divalent radical —C(O)N(CH3)C(O)—which forms together with the carbon atoms to which they are attached a 5-membered heterocyclic ring;
- and
- the bond between C2 and C3 is a single bond;
- or
- the bond between C2 and C3 together with the dotted line represents a double bond;
- an active ingredient, water and an emulsifier at room temperature;
- b. adding an ruthenium catalyst to the mixture resulting from step a);
- c heating the mixture resulting from step b);
- and
- d. optionally washing the polymer particles after the polymerisation reaction is completed.
Dependencies are inferred from the claim text.