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US 2009/0022706 A1Published application
Substituted cyclohexenes
AssigneeAuspex Pharmaceuticals, Inc.
InventorsThomas G. Gant, Sepehr Sarshar, Chengzhi Zhang
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Abstract
Disclosed herein are substituted cyclohexene TLR4 signaling pathway modulators of Formula I, process of preparation thereof, pharmaceutical compositions thereof, and methods of use thereof.
Claims62
A compound having structural Formula I
- or a pharmaceutically acceptable salt, solvate, or prodrug thereof;
- wherein:
- R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, and R17 are independently selected from the group consisting of hydrogen and deuterium;
- and
- at least one of R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, and R17 is deuterium.
2 more elements
Dependencies are inferred from the claim text.