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US 2009/0022664 A1Published application
Radiolabelling via fluorination of aziridines
OwnerAnanth Srinivasan, Thomas Brumby +5inventors
InventorsAnanth Srinivasan, Thomas Brumby, Timo Stellfeld, Keith Graham, Ulrike Voigtmann, Jessica Becaud, Linjing Mu
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Abstract
The present invention relates to novel compounds suitable for or already radiolabelled with 18F, methods of making such compounds and use of such compounds for diagnostic imaging.
Claims35
A compound comprising an aziridine ring being appropriately activated for labelling purposes, wherein a targeting agent radical, either directly or via an appropriate linker, is attached either to the aziridine ring or to a five-membered carbocyclic or heterocyclic ring which is fused to the aziridine ring.
Dependencies are inferred from the claim text.