Nebulizer with Nanometric Flow Rate of a Liquid Effluent and Nebulizing Installation Comprising Same

An installation for nebulizing liquid effluents in increments of successive volumes, said installation including at least, in series:

• a generator of a calibrated flow of at least one liquid effluent at a substantially continuous flow rate of less than 1 μl/min;
• a controlled valve that receives said calibrated flow of this liquid effluent and that makes it possible to deliver, by temporal sampling control of this calibrated flow, at least one volume element of this liquid effluent;
• and
• a nebulizer with nanoscale flow rate, including at least, arranged substantially concentrically:
• a capillary tube for intake of said liquid effluent and a nebulizing needle comprising a central channel fed with liquid effluent by said capillary tube;
• and
• a chamber for intake of said nebulizing gas feeding a nozzle for expelling said nebulizing gas, said nebulizing needle passing through said intake chamber and said nozzle for expelling said nebulizing gas, said nebulizing needle comprising an outlet orifice for said liquid effluent of which the opening diameter is less than 20 μm, the ratio of the diameter of the outlet opening of said nozzle for expelling the nebulizing gas to the outlet orifice of the nebulizing needle being greater than 10, said nebulizer receiving at least one volume element of at least one liquid effluent via a line for connection to said controlled valve and that delivers at least one volume element of nebulized liquid effluent.