Phosphonic compounds and methods of use thereof
AssigneeUnichem Technologies, Inc.
InventorAtif M. Dabdoub
Life of this patent
Estimating the term…
Abstract
Described herein are methods for producing phosphonic compounds and compounds thereof. Stable compositions of unsaturated phosphonic acid monomers are also described. Additionally, the synthesis and use of new polymers produced from phosphonic acid monomers are presented.
Claims29
A polymer produced by the process comprising polymerizing a monomer comprising the formula IV
- wherein R1-R4 and R7 comprises, independently, hydrogen, an alkyl group, a cycloalkyl group, a heteroalkyl group, a heterocycloalkyl group, an aryl group, a heteroaryl group, a protecting group, or a combination thereof, or R2 and R4 form a substituted or unsubstituted cycloalkyl group, wherein the polymer is not polyisopropenylphosphonic acid.
A method for making a polymer comprising polymerizing alone or in combination with one or more other monomers a monomer comprising the formula IV
- wherein R1-R4 and R7 comprises, independently, hydrogen, an alkyl group, a cycloalkyl group, a heteroalkyl group, a heterocycloalkyl group, an aryl group, a heteroaryl group, a protecting group, or a combination thereof, wherein the polymerization product is not polyisopropenylphosphonic acid.
A method for producing a stable composition of a monomer comprising the formula IV
- wherein R1-R4 and R7 comprises, independently, hydrogen, an alkyl group, a cycloalkyl group, a heteroalkyl group, a heterocycloalkyl group, an aryl group, a heteroaryl group, a protecting group, or a combination thereof, or R2 and R4 form a substituted or unsubstituted cycloalkyl group, the method comprising treating a mixture comprising
- with water for a sufficient time to substantially convert the dimer VII to monomer IV.
A compound comprising the formula X
- wherein R1-R4, R7, R10, and R11 comprises, independently, hydrogen, an alkyl group, a cycloalkyl group, a heteroalkyl group, a heterocycloalkyl group, an aryl group, a heteroaryl group, a protecting group, or a combination thereof, or
- R2 and R4 form a substituted or unsubstituted cycloalkyl group.
A method for making a compound comprising the formula X
- wherein R1-R4, R7, R10, and R11 comprises, independently, hydrogen, an alkyl group, a cycloalkyl group, a heteroalkyl group, a heterocycloalkyl group, an aryl group, a heteroaryl group, a protecting group, or a combination thereof, or R2 and R4 form a substituted or unsubstituted cycloalkyl group, the method comprising reacting a compound comprising the formula IV
- with H3PO3, a monoester of H3PO3, or a diester of H3PO3.
A monomer comprising the formula IV
- wherein R1-R4 and R7 comprises, independently, hydrogen, an alkyl group, a cycloalkyl group, a heteroalkyl group, a heterocycloalkyl group, an aryl group, a heteroaryl group, a protecting group, or a combination thereof, or R2 and R4 form a substituted or unsubstituted cycloalkyl group, wherein at least one of R2, R3, or R4 is a heteroalkyl group.
Dependencies are inferred from the claim text.