Delay insensitive SVD algorithm for perfusion analysis

A computerized method comprising:

• accessing a stored time sequence of volumetric image data, wherein the stored image data is obtained in a time relation to arrival of a contrast agent at a region of a subject;
• receiving a representation of at least a portion of an artery in the stored image data and a representation of tissue near the artery in the image data;
• shifting the representation of the artery in time such that a time of arrival of the contrast at the artery precedes arrival of the contrast at the representation of tissue;
• automatically computing a perfusion parameter using the shifted representation of the artery;
• and
• providing the perfusion parameter as an output to a user or to an automated process.

A computer-readable medium comprising instructions configured to perform a process comprising:

• accessing a stored time sequence of image data, wherein the stored image data is obtained in a time relation to arrival of a contrast agent at a region of a subject;
• receiving a representation of at least a portion of an artery in the stored image data;
• shifting the representation of the artery curve in time such that a time of arrival of contrast at the artery precedes arrival of contrast at the representation of tissue;
• automatically computing a perfusion parameter using the shifted representation of the artery;
• and
• providing the perfusion parameter as an output to a user or to an automated process.