Treatment for Autoimmune and Inflammatory Conditions

A method for preventing or delaying the onset of an autoimmune or inflammatory disease in a subject, the method comprising administering to the subject an effective amount of activated Protein C or precursor Protein C.

A method for preventing or reducing inflammation in a subject suffering from an autoimmune or inflammatory disease, the method comprising administering to the subject an effective amount of activated Protein C or precursor Protein C.

A method for preventing or delaying the onset of a glucose-associated condition in a subject, the method comprising administering to the subject an effective amount of activated Protein C or precursor Protein C.

A method for preventing or delaying the onset of diabetes in a subject, the method comprising administering to the subject an effective amount of activated Protein C or precursor Protein C.

A method for inhibiting the migration of leukocytes in a subject, the method comprising administering to the subject an effective amount of activated Protein C or precursor Protein C.

A method as claimed in any one of the preceding claims wherein the protein or nucleic acid construct is administered in the form of a composition together with one or more pharmaceutically acceptable carriers, adjuvants or diluents.

A composition when used for preventing the elevation of blood glucose levels, the composition comprising activated Protein C or precursor Protein C together with one or more pharmaceutically acceptable carriers, diluents or adjuvants.

A composition when used for preventing or delaying the onset of an autoimmune or inflammatory disease, the composition comprising activated Protein C or precursor Protein C together with one or more pharmaceutically acceptable carriers, diluents or adjuvants.

A composition when used for preventing or reducing inflammation in a subject suffering from an autoimmune or inflammatory disease, the composition comprising activated Protein C or precursor Protein C together with one or more pharmaceutically acceptable carriers, diluents or adjuvants.

A composition when used for preventing or delaying the onset of a glucose-associated condition, the composition comprising activated Protein C or precursor Protein C together with one or more pharmaceutically acceptable carriers, diluents or adjuvants.

A composition when used for preventing or delaying the onset of diabetes, the composition comprising activated Protein C or precursor Protein C together with one or more pharmaceutically acceptable carriers, diluents or adjuvants.

A composition when used for inhibiting migration of leukocytes, the composition comprising activated Protein C or precursor Protein C together with one or more pharmaceutically acceptable carriers, diluents or adjuvants.

Use of activated Protein C or precursor Protein C for the manufacture of a medicament for the prevention of elevation of blood glucose levels in a subject.

Use of activated Protein C or precursor Protein C for the manufacture of a medicament for preventing or delaying the onset of an autoimmune or inflammatory disease in a subject.

Use of activated Protein C or precursor Protein C for the manufacture of a medicament for preventing or delaying the onset of a glucose-associated condition.

Use of activated Protein C or precursor Protein C for the manufacture of a medicament for preventing or delaying the onset of diabetes.