Methods and compositions for diagnosing neoplastic disease
AssigneeInvitrogen Corporation
InventorOzge ALPER
Life of this patent
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Abstract
Methods and compositions for determining whether a subject at least has a neoplastic disease are provided. In practicing the subject methods, a sample from a subject is assayed for a soluble filamin analyte, such as a filamin A analyte, to determine whether the subject at least has the neoplastic disease. Also provided are kits, systems, and devices for practicing the subject methods.
Claims38
A method of diagnosing whether a subject has a neoplastic disease, said method comprising:
- assaying an extracellular sample from said subject for a soluble filamin analyte to diagnose whether said subject has said neoplastic disease.
A method of treating a subject having a neoplastic disease, said method comprising:
- (a) diagnosing whether said subject suffers from a neoplastic disease by assaying an extracellular sample from said subject for a soluble filamin analyte;
- and
- (b) treating said subject based on results from said diagnosing step (a).
A kit for use in diagnosing whether a subject has a neoplastic disease, comprising:
- reagents for assaying a sample for a soluble filamin analyte;
- and
- a reference.
A system for use in diagnosing whether a subject has a neoplastic disease, comprising:
- reagents for assaying a sample for a soluble filamin analyte;
- and
- a reference.
A device for use in diagnosing whether a subject suffers from a neoplastic disease, said device comprising:
- a soluble filamin analyte specific affinity reagent immobilized on a surface of a solid support.
An antibody that specifically binds to a soluble form of a filamin analyte.
The cell according to claim 38, wherein said cell is a hybridoma cell.
Dependencies are inferred from the claim text.