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AssigneeGevo, Inc.
InventorsEzhilkani Subbian, Peter Meinhold, Thomas Buelter, Andrew C. Hawkins
Estimating the term…
In an embodiment, there is disclosed a recombinant microbial host cell having each of the DNA molecules encoding a polypeptide or group of polypeptides that catalyze the conversion: (i) Acetyl-CoA to Acetate and CoA (conversion 1) (ii) Acetyl-CoA to Acetoacetyl-CoA and CoA (conversion 2) (iii) Acetoacetyl-CoA and Acetate to Acetoacetate and Acetyl-CoA (conversion 3.1) (iv) Acetoacetate to Acetone and CO2 (conversion 4) (v) Acetone and NAD(P)H and H+ to Isopropanol and NAD(P)+ (conversion 5) wherein at least one DNA molecule is heterologous to the microbial host cell and wherein the microbial host cell produces isopropanol. In another embodiment, a method is disclosed for the production of isopropanol including providing a recombinant microbial host cell, the host cell of (i) with a fermentable carbon substrate in a fermentation medium under conditions whereby isopropanol is produced, and recovering the isopropanol.
A recombinant microbial host cell comprising each of the DNA molecules encoding a polypeptide or group of polypeptides that catalyze the conversion:
A recombinant microbial host cell comprising each of the DNA molecules encoding a polypeptide that catalyzes the conversion:
33-59. (canceled)
A method for the production of isopropanol comprising:
61-84. (canceled)
An isopropanol containing fermentation medium produced by a method comprising:
Isopropanol produced by a method comprising:
A method for the production of isopropanol comprising:
88-108. (canceled)
An isopropanol containing fermentation medium produced by a method comprising:
Isopropanol produced by a method comprising:
Dependencies are inferred from the claim text.