Chip for Diagnosing the Presence of Candida
AssigneesFrauhofer-Gesellschaft Zur Foerderung Der Angewandtten Forschung e.V., Universitaet Stuttgart
InventorsNicole Hauser, Steffen Rupp, Achim Weber, Guenter Tovar, Ekkehard Hiller, Kirsten Borchers
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Abstract
The present invention concerns means and methods of detection of Candida and Candida-related fungal cells in clinical material by means of protein biochips.
Claims17
A Candida diagnosis chip, comprising a substrate with a surface and at least one microstructure arranged on the substrate surface with molecule-specific recognition sites immobilized thereon, wherein the molecule-specific recognition sites are selected from:
- a) specific antibodies against protein TSA, and
- b) protein TSA.
A method for the preparation of a Candida diagnosis chip, comprising the steps of:
- a) preparing a substrate with a surface, and
- b) depositing at least one microstructure on the surface of the substrate, wherein the microstructure contains at least two nanoparticles, on which are immobilized proteins with molecule-specific recognition sites selected from:
- i) specific antibodies to the protein TSA, and
- ii) protein TSA.
(canceled)
Dependencies are inferred from the claim text.