Polymer-Based Serum Albumin Substitute
AssigneeThe University of British Columbia
InventorsDonald E. Brooks, Jayachandran N. Kizhakkedathu, Rajesh Kumar Kainthan
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Abstract
This invention provides the use of a polymer comprising a hyperbranched polyether polyol such as hyperbranched polyglycerol as a serum albumin substitute. Also provided are high molecular weight hyperbranched polyglycerol polymers suitable for a variety of medical and non-medical uses including methods for making such high molecular weight polymers.
Claims82
A method of treating a human or non-human animal to preserve living tissue or an organ by administering a polymer comprising a hyperbranched polyether polyol as a substitute for serum albumin.
(canceled)
A sterile composition comprising a polymer and at least one physiologically acceptable salt, buffer, diluent or excipient, for use as a blood or plasma expander, replacement or substitute, wherein the polymer comprises a hyperbranched polyether polyol.
A hyperbranched polyglycerol (HPG) having a molecular weight of over 95,000 g/mol and a polydispersity of about 1 to about 3.5.
Dependencies are inferred from the claim text.