Derivatives of artemisinin, and their uses in the treatment of malaria

A compound of the formula

• in which:
• R1 is:
• a fluoroalkyl group of 1 to 5 carbon atoms, comprising at least two fluorine atoms, selected from the perfluoroalkyl group consisting of CF3, C2F5, C3F7, C4F9, and C5F11, or
• a fluoroaryl group comprising at least two fluorine atoms, selected from the group comprising the perfluoroaryl group C6F5,
• R2 is a hydrogen atom, a halogen atom, or a group that renders said compound water-soluble, said group derived from piperazine, morpholine, alkylamine, alkoxy, ester or diester, acid or diacid, thioalkyl, alkylhydroxyl, or glycosyl,
• R3 is:
• an OR group, in which R is H, an alkyl group of 1 to 10 carbon atoms or a phenyl group, or
• NH2 or a NH—R6 group, in which R6 is an alkyl or alkoxy group of 1 to 5 carbon atoms, an arylalkyl group or arylalkoxy group, and
• is H or OH.