US 2008/0280976 A1 · Composition Comprising the Alcohol Compound Isolated from the Extract of Cucurbitaceae Family Plant Having Anti-Adipogenic and Anti-Obesity Activity

Abstract

The present invention is related to an alcohol compound isolated from the extract of Cucurbitaceae family plant having anti-adipogenic and anti-obesity activity, and a composition comprising the same. The compound showed potent reducing activity of body weight, decreasing effect on the blood triglyceride and cholesterol level, activating activity of PPAR α and preventing activity from the adipogenesis of precursor fat cells with no toxicity, therefore, those extract can be useful in treating or preventing obesity and adipogenesis-involved diseases as a medicine or health care food.

Claims6

Dependent claims

A method to induce an anti-obesity effect comprising the step of administering an effective amount of dehyrodiconiferyl alcohol (DHCA) of formula (Ia) into a subject in need thereof,

wherein the anti-obesity effect is selected from the group consisting of (i) inhibiting adipocyte differentiation, (ii) inhibiting triglyceride synthesis, (iii) activating PPAR alpha and (iv) reducing body weight

Dependencies are inferred from the claim text.

Facts

Application

12/124,131Filed 20 May 2008

Priority

KR 10-2003-00872753 Dec 2003

Published

13 Nov 2008

Term ends

Not estimatedThe source records don’t support an estimate.

Classification9 codes

A61K 36/42
Magnoliopsida: cucurbitaceae
A23L 33/105
Using additives: plant extracts, their artificial duplicates or their derivatives
A61K 31/343
Having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide: condensed with a carbocyclic ring, e.g. coumaran,…
A61P 3/00
Drugs for disorders of the metabolism

Composition Comprising the Alcohol Compound Isolated from the Extract of Cucurbitaceae Family Plant Having Anti-Adipogenic and Anti-Obesity Activity

Life of this patent

Composition Comprising the Alcohol Compound Isolated from the Extract of Cucurbitaceae Family Plant Having Anti-Adipogenic and Anti-Obesity Activity

Life of this patent

Abstract

Claims6