# US 2008/0188933 A1 · Woven and/or braided fiber implants and methods of making same > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2008/0188933 A1 - Document ID: US20080188933A1 - Status: Published application - Kind: A1 - Application number: 11/964,745 - Filed: 2007-12-27 - Published: 2008-08-07 - Earliest claimed: 2006-12-27 - Assignees: Shriners Hospitals for Children - Inventors: Thomas J. Koob; Tian Davis; Douglas Pringle - Web page: https://patentgrep.com/patent/US20080188933A1 ## CPC - C07K 14/78: Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG] - A61L 27/24: Collagen - D06M 13/152: having a hydroxy group bound to a carbon atom of a six-membered aromatic ring - D06M 2101/14: Collagen fibres - C07K: PEPTIDES (peptides in foodstuffs A23; obtaining protein compositions for foodstuffs, working-up proteins for foodstuffs A23J; preparations for medicinal purposes A61K; peptides containing beta-lactam rings C07D; cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, C07D; ergot alkaloids of the cyclic peptide type C07D519/02; macromolecular compounds having statistically distributed amino acid units in their molecules, i.e. when the preparation does not provide for a specific; but for a random sequence of the amino acid units, homopolyamides and block copolyamides derived from amino acids C08G69/00; macromolecular products derived from proteins C08H1/00; preparation of glue or gelatine C09H; single cell proteins, enzymes C12N; genetic engineering processes for obtaining peptides C12N15/00; compositions for measuring or testing processes involving enzymes C12Q; investigation or analysis of biological material G01N33/00) - A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K) - D06M: TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS ## Abstract The disclosure describes implantable bioprosthesis having an implantable braided or woven construct with a plurality of fibers interlocked or interlaced together. ## Claims ### Claim 1 An implantable bioprosthesis, comprising: an implantable construct having a plurality of synthetic fibers braided and/or woven together. ### Claim 2 (depends on 1) A bioprosthesis according to claim 1, wherein the fibers are NDGA polymerized collagen fibers. ### Claim 3 (depends on 1) A bioprosthesis according to claim 1, wherein the plurality of fibers are collagen-derived fibers, and wherein the plurality of fibers are a plurality of bundles of fibers that are braided and/or woven together, each of the bundles of fibers comprising at least two fibers. ### Claim 4 (depends on 3) A bioprosthesis according to claim 3, wherein the plurality of bundles of fibers is at least three. ### Claim 5 (depends on 4) A bioprosthesis according to claim 4, wherein the plurality of bundles of fibers is between about six to about twenty-seven. ### Claim 6 (depends on 4) A bioprosthesis according to claim 4, wherein the plurality of bundles is nine. ### Claim 7 (depends on 4) A bioprosthesis according to claim 4, wherein the plurality of fibers in at least some of the bundles is between about 6 to about 11 fibers. ### Claim 8 (depends on 4) A bioprosthesis according to claim 4, wherein the plurality of fibers in each bundle is about nine. ### Claim 9 (depends on 8) A bioprosthesis according to claim 8, wherein the plurality of fibers in each bundle are substantially parallel with each other. ### Claim 10 (depends on 1) A bioprosthesis according to claim 1, wherein the construct is between about 1-3 cm long. ### Claim 11 (depends on 9) A bioprosthesis according to claim 9, wherein the construct is between about 0.1 cm to about 3 cm wide. ### Claim 12 (depends on 1) A bioprostheis according to claim 1, wherein the construct has a substantially flat ribbon configuration sized and configured to define a ligament bioprosthesis. ### Claim 13 (depends on 12) A bioprostheis according to claim 12, wherein the ligament bioprothesis is an ACL bioprosthesis. ### Claim 14 (depends on 1) A bioprostheis according to claim 1, wherein the construct has a substantially tubular rope configuration sized and configured to define a tendon bioprosthesis. ### Claim 15 (depends on 14) A bioprosthesis according to claim 14, wherein the tendon bioprosthesis is a flexor tendon bioprosthesis. ### Claim 16 (depends on 12) A bioprosthesis according to claim 12, wherein the construct has a tensile strength, stiffness and dynamic flexibility that meets or exceeds that of a pre-injury natural ligament undergoing treatment. ### Claim 17 (depends on 14) A bioprosthesis according to claim 14, wherein the braided construct has a tensile strength, stiffness and dynamic flexibility that meets or exceeds that of a pre-injury natural tendon undergoing treatment. ### Claim 18 (depends on 1) A bioprosthesis according to claim 1, wherein the braided construct includes a gel material. ### Claim 19 (depends on 1) A bioprosthesis according to claim 1, wherein at least one end portion of the construct includes at least two split segments of fibers that are configured as bone or tissue attachment segments. ### Claim 20 A method of making a bioprosthesis, comprising: providing a plurality of discrete bundles of fibers; and braiding and/or weaving the bundles into an interlocking braid pattern to form a bioprosthesis construct. ### Claim 21 (depends on 20) A method according to claim 20, wherein the fibers comprise NDGA polymerized collagen fibers. ### Claim 22 (depends on 20) A method according to claim 20, wherein the plurality of discrete bundles of fibers are arranged to be substantially parallel to each other in a respective bundle. ### Claim 23 (depends on 22) A method according to claim 22, wherein the interlocking braid or weave pattern forms a substantially flat bioprosthesis construct. ### Claim 24 (depends on 22) A method according to claim 22, wherein the interlocking braid or weave pattern forms a substantially tubular bioprosthesis construct. ### Claim 25 (depends on 20) A method according to claim 20, further comprising forming at least two split segments of a group of fibers in at least one end portion of the braided bioprosthesis construct. ### Claim 26 A medical kit for a tendon or ligament repair, augmentation or replacement, comprising: a braided or woven NDGA collagen fiber construct; and a sterile package sealably enclosing the braided fiber construct therein. ### Claim 27 (depends on 26) A medical kit according to claim 26, wherein the construct has a substantially flat configuration. ### Claim 28 (depends on 27) A medical kit according to claim 27, wherein the construct is a bioprosthesis ligament for a ligament repair, augmentation or replacement. ### Claim 29 (depends on 26) A medical kit according to claim 26, wherein the construct has a substantially tubular braided rope configuration and is a bioprosthesis for a tendon repair, augmentation or replacement.