# US 2008/0188923 A1 · Endovascular devices to protect aneurysmal wall > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2008/0188923 A1 - Document ID: US20080188923A1 - Status: Published application - Kind: A1 - Application number: 12/021,249 - Filed: 2008-01-28 - Published: 2008-08-07 - Earliest claimed: 2007-02-01 - Inventors: Jack Fa-De Chu - Web page: https://patentgrep.com/patent/US20080188923A1 ## CPC - A61F 2/07: Stent-grafts - A61B 17/12118: {for positioning in conjunction with a stent} - A61B 17/12136: {Balloons} - A61B 17/1219: {expandable in contact with liquids} - A61B 17/12195: {comprising a curable material} - A61B 17/12022: {Occluding by internal devices, e.g. balloons or releasable wires (plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20)} - A61F 2/89: the wire-like elements comprising two or more adjacent rings flexibly connected by separate members - A61F 2002/072: {Encapsulated stents, e.g. wire or whole stent embedded in lining} - A61F 2002/075: {the stent being loosely attached to the graft material, e.g. by stitching} - A61F 2002/077: {having means to fill the space between stent-graft and aneurysm wall, e.g. a sleeve} - A61F 2230/0071: spherical - A61F 2250/0003: having an inflatable pocket filled with fluid, e.g. liquid or gas - A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C) - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) ## Abstract Methods and systems for preventing aneurysm rupture and reducing the risk of migration and endoleak are disclosed. Specifically, an inflatable multiple walls liner is applied directly to treat the interior of the aneurysm site. Also disclosed are methods to deliver the inflatable multiple walls liner directly to treatment sites. ## Claims ### Claim 1 A system to protect the wall of an aneurysm in a vessel wherein the system comprises: a liner comprising one or more inflatable chambers for the introduction of an inflation medium, said one or more inflatable chambers comprising one or more connectors, wherein said liner is configured to conform to the interior surface of the aneurysm following introduction of said liner into the vessel, and wherein said one or more connectors constrains expansion of said one or more chambers upon introduction of said inflation medium. ### Claim 2 (depends on 1) The system as set forth in claim 1 further comprising means for anchoring said liner to the interior of the vessel. ### Claim 3 (depends on 2) The system as set forth in claim 2, wherein said means for anchoring said liner comprises one or more expandable elements coupled to said liner. ### Claim 4 (depends on 3) The system as set forth in claim 3, wherein said one or more expandable elements comprises a stent. ### Claim 5 (depends on 1) The system as set forth in claim 1, wherein one or more of said inflatable chambers comprises one or more opposing interior walls and said one or more connectors is affixed to opposing interior walls. ### Claim 6 (depends on 5) The system as set forth in claim 5, wherein said one or more connectors comprises a strip, a string, or a bond. ### Claim 7 (depends on 1) The system as set forth in claim 1, wherein said one or more inflatable chambers comprises an inflatable patch or an inflatable channel. ### Claim 8 (depends on 1) The system as set forth in claim 1, wherein said one or more inflatable chambers is disposed helically on the exterior of said liner. ### Claim 9 (depends on 1) The system as set forth in claim 1, wherein said one or more inflatable chambers is disposed circumferentially on the exterior of said liner. ### Claim 10 (depends on 1) The system as set forth in claim 1, wherein the said liner comprises flexible and substantially inelastic biocompatible material. ### Claim 11 (depends on 1) The system as set forth in claim 1, wherein one or more inflatable chambers is in fluid communication with one or more adjacent inflatable chambers. ### Claim 12 (depends on 1) The system as set forth in claim 1 further comprising a one way valve in fluid communication with one or more inflatable chambers. ### Claim 13 (depends on 1) The system as set forth in claim 1, wherein said liner comprises an inner wall defining a main flow conduit of the vessel proximate the aneurysm following introduction of the liner into the vessel, said conduit comprising an inlet and one or more outlets. ### Claim 14 (depends on 13) The system as set forth in claim 13, wherein said main flow conduit is defined by the inner surface of the aneurysm, said connectors and the amount inflation medium in said liner. ### Claim 15 (depends on 1) The system as set forth in claim 1, wherein the inflation medium comprises a fluid comprising a polymer, an oligomer or a monomer. ### Claim 16 (depends on 1) The system as set forth in claim 1, wherein the inflation medium comprises a fluid selected from the group consisting of silicone, hydrogel, saline, water, blood, polyvinyl alcohol, cyanoacrylate, methacrylate, acrylate, polyacrylic acid polymer, polyacrylamide, polyvinyl pyrrolidone, polyacrylonitrile, Hypan, poly(2-hydroxyethyl methacrylate), polyethylene oxide, poly(propylene oxide), poly(ethylene glycol), poly(propylene glycol), Poloxamer, Pluronic, and Tetronics. ### Claim 17 (depends on 1) The system as set forth in claim 1 wherein said inflation medium comprises a fluid, and wherein the fluid is curable by either chemical or physical means after injection into the liner. ### Claim 18 (depends on 1) The system as set forth in claim 1 wherein said inflation medium comprises a fluid, and said fluid comprises a bioactive or a pharmaceutical active component. ### Claim 19 (depends on 1) The system as set forth in claim 1, wherein the liner comprises an outer surface comprising a bioactive or a pharmaceutical active component. ### Claim 20 (depends on 1) The system as set forth in claim 1, wherein the liner comprises an outer surface and surface area, wherein said outer surface is treated with fibers, fibril, foam, or roughening to increase the surface area. ### Claim 21 (depends on 1) The system as set forth in claim 1 further comprising means to introduce a hemodynamic force in said liner whereby said liner expands and conforms to the interior surface of the aneurysm. ### Claim 22 A system to protect the wall of an aneurysm in a vessel wherein the system comprises: an inflatable multiple walls liner having an inner wall and an outer wall, wherein said inner wall and outer wall being connected by one or more connectors to form one or more inflatable chambers to be filled by an inflation medium, wherein said liner is configured to conform to the interior surface of the aneurysm by a hemodynamic force in the vessel, and wherein said one or more connectors constrains expansion of said one or more chambers upon introduction of said inflation medium. ### Claim 23 (depends on 22) The system as set forth in claim 22 further comprising means for anchoring said liner to the interior of the vessel. ### Claim 24 (depends on 23) The system as set forth in claim 23, wherein said means for anchoring said liner comprises one or more expandable elements coupled to said liner. ### Claim 25 A method of treatment of an aneurysm comprising: providing an inflatable liner comprising one or more inflatable chambers; and anchoring a portion of the inflatable liner in the vessel adjacent the aneurysm with a first expandable element and introducing hemodynamic force in the inflatable liner whereby said liner expands and conforms to the interior surface of the aneurysm. introducing inflation medium into the one or more inflatable chambers whereby said liner expands and protects the vessel. ### Claim 26 A method of treatment of an aneurysm of a subject vessel wherein the vessel comprises an interior, an interior surface and a hemodynamic force therethrough, the method comprising: providing an inflation medium, one or more expandable elements and an inflatable liner comprising one or more inflatable chambers, one or more flow conduit outlets; introducing said inflatable liner into the vessel; anchoring the inflatable liner within the vessel proximate the aneurysm via deployment of one or more expandable elements; permitting the hemodynamic force to expand said inflatable liner to substantially conform to the interior surface of the vessel; securing patency of one or more of said flow conduit outlets via deployment of one or more expandable elements; introducing said inflation medium into the one or more inflatable chambers; and removing one or more expandable elements. ### Claim 27 (depends on 26) The method as set forth in claim 26 further comprising the steps of: providing one or more stents; introducing one or more stents into the inflatable liner; and deploying one or more stents within the inflatable liner. ### Claim 28 (depends on 26) The method as set forth in claim 26, wherein said step of anchoring said inflatable liner via deployment of said expandable element permits fluid perfusion therethrough and substantially prevents fluid flow between said inflatable liner and the interior surface of said vessel following deployment of said expandable element. ### Claim 29 (depends on 28) The method as set forth in claim 28, wherein said expandable element is a balloon, a balloon comprising an annular shape or a stent. ### Claim 30 (depends on 26) The method as set forth in claim 26, wherein said one or more expandable elements in said step of securing patency of one or more of said flow conduit outlets comprise a balloon, a balloon comprising an annular shape, or a stent. ### Claim 31 (depends on 26) The method as set forth in claim 26, wherein said inflatable liner further comprising one or more stents. ### Claim 32 (depends on 26) The method as set forth in claim 26 further comprising the step of; allowing the perfusion of fluid between said inflatable liner and said one or more expandable elements via reducing the size of said one or more expandable elements. ### Claim 33 A method of treatment of an aneurysm of a subject vessel wherein the vessel comprises an interior, an interior surface and a hemodynamic force therethrough, the method comprising: providing an inflation medium, one or more expandable elements and an inflatable liner comprising one or more inflatable chambers, one or more flow conduit outlets and one or more stents; introducing said inflatable liner into the vessel; anchoring the inflatable liner within the vessel proximate the aneurysm via deployment of one or more stents; permitting the bemodynamic force to expand said inflatable liner to substantially conform to the interior surface of the vessel; securing patency of one or more of said flow conduit outlets via deployment of one or more expandable elements; introducing said inflation medium into the one or more inflatable chambers; and removing one or more expandable elements. ### Claim 34 (depends on 33) The method as set forth in claim 33 further comprising the steps of: providing one or more stents; introducing one or more stents into the inflatable liner; and deploying one or more stents within the inflatable liner. ### Claim 35 (depends on 33) The method as set forth in claim 33, wherein said step of anchoring said inflatable liner via deployment of said one or more stents permits fluid perfusion therethrough and substantially prevents fluid flow between said inflatable liner and the interior surface of said vessel following deployment of said one or more stents. ### Claim 36 (depends on 33) The method as set forth in claim 33, wherein said one or more expandable elements in said step of securing patency of one or more of said flow conduit outlets comprise a balloon, a balloon comprising an annular shape, or a stent. ### Claim 37 (depends on 33) The method as set forth in claim 33 further comprising the steps of: deploying one or more expandable elements within the inflatable liner proximate the aneurysm; allowing the perfusion of fluid between said inflatable liner and said one or more expandable elements via reducing the size of said one or more expandable elements.