# US 2008/0188731 A1 · Transcutaneous analyte sensor > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2008/0188731 A1 - Document ID: US20080188731A1 - Status: Published application - Kind: A1 - Application number: 12/101,806 - Filed: 2008-04-11 - Published: 2008-08-07 - Earliest claimed: 2004-07-13 - Assignees: DexCom, Inc. - Inventors: Mark Brister; Paul V. Neale; James Brauker - Web page: https://patentgrep.com/patent/US20080188731A1 ## CPC - A61B 5/14532: {for measuring glucose, e.g. by tissue impedance measurement} - A61B 5/0002: {Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network (endoradiosondes A61B5/07)} - A61B 5/0004: {characterised by the type of physiological signal transmitted} - A61B 5/0031: {Implanted circuitry} - A61B 5/05: Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves (measuring movement of the entire body or parts thereof A61B5/11; detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof A61B5/24) - A61B 5/1411: {by percutaneous method, e.g. by lancet} - A61B 5/14503: {invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors (A61B5/1459, A61B5/1464, A61B5/1473, A61B5/1482, A61B5/14865 take precedence)} - A61B 5/14507: {specially adapted for measuring characteristics of body fluids other than blood (devices for taking samples of body liquids A61B10/0045)} - A61B 5/1451: {for interstitial fluid} - A61B 5/14514: {using means for aiding extraction of interstitial fluid, e.g. microneedles or suction} - A61B 5/14546: {for measuring analytes not otherwise provided for, e.g. ions, cytochromes} - A61B 5/1473: invasive, e.g. introduced into the body by a catheter - A61B 5/14735: {comprising an immobilised reagent} - A61B 5/1486: using enzyme electrodes, e.g. with immobilised oxidase - A61B 5/14865: {invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors} - A61B 5/1495: Calibrating or testing of in-vivo probes - A61B 5/6801: {specially adapted to be attached to or worn on the body surface} - A61B 5/6833: {Adhesive patches} - A61B 5/68335: {including release sheets or liners} - A61B 5/6848: {Needles} - A61B 5/6849: {in combination with a needle set} - A61B 5/72: {Signal processing specially adapted for physiological signals or for diagnostic purposes} - A61B 17/3468: {for implanting or removing devices, e.g. prostheses, implants, seeds, wires (devices for implanting seeds A61M37/0069)} - A61B 5/14: {Devices for taking samples of blood (hypodermic syringes A61M5/00); Measuring characteristics of blood in vivo, e.g. gas concentration within the blood, pH-value of blood (measuring of blood pressure A61B5/02; non-radiation detecting or locating of foreign bodies in blood A61B5/06)} - A61B 5/145: Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value {; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue} (non-radiation detecting or locating of foreign bodies in blood A61B5/06) - A61B 5/1468: using chemical or electrochemical methods, e.g. by polarographic means - A61B 5/150022: {for capillary blood or interstitial fluid} - A61B 2017/3492: {against the outside of the body} - A61B 2560/0223: of calibration, e.g. protocols for calibrating sensors - A61B 2560/045: with a separable interface unit, e.g. for communication - A61B 2560/063: Devices specially adapted for delivering implantable medical measuring apparatus - A61B 2562/18: Shielding or protection of sensors from environmental influences, e.g. protection from mechanical damage - A61M 5/14244: {adapted to be carried by the patient, e.g. portable on the body} - A61M 5/1723: {using feedback of body parameters, e.g. blood sugar or pressure} - A61M 2005/1585: {Needle inserters} - Y02A 90/10: Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} - Y02A: TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE ## Abstract The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host. ## Claims ### Claim at position 1 1-13. (canceled) ### Claim 14 A method for inserting a transcutaneous analyte sensor into a host using an applicator, the method comprising the steps of: pushing on a first component of an applicator for inserting a transcutaneous analyte sensor into a host, so as to insert an introducer and the sensor into the skin of the host; and pulling on a second component of the applicator so as to retract the introducer from the skin of the host, while leaving the sensor in the host; wherein the first component and the second component of the applicator are configured to interact so as to enable insertion of the sensor and retraction of the introducer using a single continuous motion provided by a user. ### Claim 15 (depends on 14) The method of claim 14, wherein the pushing step comprises pushing on a plunger. ### Claim 16 (depends on 14) The method of claim 14, wherein the pulling step comprises pulling on a collar. ### Claim 17 (depends on 14) The method of claim 14, wherein the applicator is configured to insert the sensor and retract the introducer solely by a force provided by a user's hand. ### Claim 18 (depends on 14) The method of claim 14, wherein the applicator is configured to sequentially insert the sensor and retract the introducer responsive to a squeezing motion between a user's thumb and fingers. ### Claim 19 (depends on 14) The method of claim 14, wherein the applicator is configured to sequentially insert the sensor and retract the introducer responsive to a continuous downward force provided by the user. ### Claim 20 (depends on 14) The method of claim 14, wherein the components of the applicator rotatingly engage so as to insert the sensor and retract the introducer by a torque. ### Claim 21 (depends on 14) The method of claim 14, wherein the user is the host. ### Claim 22 A method for inserting a transcutaneous analyte sensor into a host using an applicator, the method comprising the steps of: placing an applicator system against a skin of a host, the applicator system comprising a housing configured for placement against the skin of the host, a sensor configured for transcutaneous placement through the skin of a host, and an applicator configured for inserting the sensor through the housing and into the skin of the host; and inserting the sensor into the host by applying a torque to a component of the applicator. ### Claim 23 A method of using an electrochemical sensor, the method comprising: adhering a mounting unit to a skin of a patient, wherein the mounting unit comprises an applicator coupled thereto, the applicator having an electrochemical sensor disposed therein; inserting an electrochemical sensor into the skin of the patient using the applicator; releasing the applicator; and coupling an electronics unit body to the mounting unit, whereby a plurality of conductive contacts disposed on the mounting unit are coupled with a plurality of conductive contacts disposed on the electronics unit body. ### Claim 24 A method, comprising the step of: retaining an analyte sensor within an introducer during the sensor insertion into a patient such that the sensor is positioned at a relatively fixed position with respect to the introducer. ### Claim 25 (depends on 24) The method of claim 24, further including the step of: positioning the sensor to be in fluid contact with a biological fluid of a patient.