# US 2008/0188688 A1 · Solvents for phase-transfer-catalyzed reactions

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- Number: US 2008/0188688 A1
- Document ID: US20080188688A1
- Status: Published application
- Kind: A1
- Application number: 12/024,363
- Filed: 2008-02-01
- Published: 2008-08-07
- Earliest claimed: 2007-02-02
- Inventors: Hendrik Huesken; Paul Birnbrich; Rainer Hoefer
- Web page: https://patentgrep.com/patent/US20080188688A1

## CPC

- C07B 61/00: Other general methods
- C07C 45/68: by increase in the number of carbon atoms
- C07B: GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR (preparation of carboxylic acid esters by telomerisation C07C67/47; telomerisation C08F)
- C07C: ACYCLIC OR CARBOCYCLIC COMPOUNDS

## Abstract

A process for the production of organic substances, including the steps of providing at least a two-phase system, in which selected reactants are reacted in the presence of a phase transfer catalyst, where one of the phases is an organic solvent with a log P value, at 20° C., of more than 2.6, is provided.

## Claims

### Claim 1

A process for the production of organic substances, comprising the steps of:
providing at least a two-phase system, in which selected reactants are reacted in the presence of a phase transfer catalyst, wherein one of the phases is an organic solvent with a log P value, at 20° C., of more than 2.6.

### Claim 2 (depends on 1)

The process according to claim 1, wherein the two-phase system comprises a water phase, and an organic solvent with a log P value of more than 2.62.

### Claim 3 (depends on 2)

The process according to claim 2, wherein the organic solvent comprises a saturated fatty acid dimethyl amide.

### Claim 4 (depends on 1)

The process according to claim 1, wherein the organic solvent has a melting point below 20° C.

### Claim 5 (depends on 1)

The process according to claim 1, wherein the organic solvent has a log P value of more than 2.8.

### Claim 6 (depends on 1)

The process according to claim 1, wherein the phase transfer catalyst is selected from the group consisting of: tetraalkyl ammonium salts, benzyl trialkyl ammonium salts, tetraalkyl phosphonium salts, benzyltrialkyl phosphonium salts, polyethylene glycols and end-capped polyethylene glycols.

### Claim 7 (depends on 2)

The process according to claim 2, wherein the phase transfer catalyst is selected from the group consisting of: tetraalkyl ammonium salts, benzyl trialkyl ammonium salts, tetraalkyl phosphonium salts, benzyltrialkyl phosphonium salts, polyethylene glycols and end-capped polyethylene glycols.

### Claim 8 (depends on 3)

The process according to claim 3, wherein the phase transfer catalyst is selected from the group consisting of: tetraalkyl ammonium salts, benzyl trialkyl ammonium salts, tetraalkyl phosphonium salts, benzyltrialkyl phosphonium salts, polyethylene glycols and end-capped polyethylene glycols.

### Claim 9 (depends on 1)

The process according to claim 1, wherein the phase transfer catalyst is an ionic liquid.
