# US 2008/0185313 A1 · Medicament regimen for treating bronchitis or lower respiratory tract condition

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- Number: US 2008/0185313 A1
- Document ID: US20080185313A1
- Status: Published application
- Kind: A1
- Application number: 11/671,155
- Filed: 2007-02-05
- Published: 2008-08-07
- Earliest claimed: 2007-02-05
- Inventors: Donna F. White
- Web page: https://patentgrep.com/patent/US20080185313A1

## CPC

- A61J 7/04: Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
- A61J: CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE

## Abstract

A therapeutic treatment regimen for a bronchitic condition or lower respiratory tract infection and method of treating same a subject in need thereof are described. The regimen comprises at least one dosage of an oral antibiotic, at least one therapeutically effective dosage of an oral adjunct medication selected from antitussives, expectorants, antihistamines, decongestants, anticholinergics, mucolytics and combinations thereof and a prepackaged dosage dispenser comprising the oral antibiotic and the oral adjunct medication. The method comprises providing a prepackaged dosage dispenser comprising an oral antibiotic and an oral adjunct medication, providing administering indicia integrated into the prepackaged dosage dispenser for administration of the oral antibiotic and oral adjunct medication.

## Claims

### Claim 1

A method of providing a treatment regimen for treating a bronchitic condition in a subject in need thereof, the method comprising:
(a) providing a prepackaged dosage dispenser comprising an oral antibiotic effective for treating the bronchitic condition and a oral adjunct medication selected from antitussives, expectorants, antihistamines, decongestants, anticholinergics, mucolytics and combinations thereof; and
(b)providing administering indicia for administering the oral antibiotic and the oral adjunct medication for treating the bronchitic condition, the indicia being integrated with the prepackaged dosage dispenser.

### Claim 2 (depends on 1)

The method of claim 1, wherein the bronchitic condition is an acute bacterial exacerbation related to chronic bronchitis.

### Claim 3 (depends on 1)

The method of claim 1, wherein the bronchitic condition is a secondary bacterial exacerbation related to acute bronchitis.

### Claim 4 (depends on 1)

The method of claim 1, wherein the treatment regimen provides for improved therapeutic compliance.

### Claim 5 (depends on 1)

The method of claim 1, wherein the treatment regimen provides for reduced medication error.

### Claim 6 (depends on 1)

The method of claim 1, wherein the at least one oral antibiotic is selected from the class of antibiotics consisting of penicillins, cephalosporins and macrolides.

### Claim 7 (depends on 1)

The method of claim 1, wherein the at least one oral antibiotic is selected from the group consisting of amoxicillin, azithromycin, cefdinir, cefditoren, cefprozil, cefuroxime and clarithromycin.

### Claim 8 (depends on 1)

The method of claim 1, wherein the at least one oral adjunct medication is selected from the group consisting of benzonatate, carbetapentane, chlorpheniramine, dextromethorphan, guaifenesin, hydrocodone, methscopolamine, phenylephrine and pseudoephedrine.

### Claim 9 (depends on 1)

The method of claim 1, wherein the at least one oral adjunct medication is a decongestant.

### Claim 10 (depends on 9)

The method of claim 9, wherein the decongestant is phenylephrine, phenylpropanolamine or pseudoephedrine.

### Claim 11 (depends on 1)

The method of claim 1, wherein the at least one oral antibiotic is selected from the group consisting of amoxicillin, azithromycin, cefdinir, cefditoren, cefprozil, cefuroxime and clarithromycin; and the at least one oral adjunct medication is phenylephrine or pseudoephedrine.

### Claim 12 (depends on 1)

The method of claim 1, wherein the oral antibiotic comprises amoxicillin/clavulanate and the oral adjunct medication comprises phenylephrine and guaifenesin.

### Claim 13 (depends on 1)

The method of claim 1, wherein the oral antibiotic comprises amoxicillin/clavulanate and the oral adjunct medication comprises pseudoephedrine.

### Claim 14 (depends on 1)

The method of claim 1, wherein the oral antibiotic comprises azithromycin and the oral adjunct medication comprises pseudoephedrine, guaifenesin and dextromethorphan.

### Claim 15 (depends on 1)

The method of claim 1, wherein the oral antibiotic comprises azithromycin and the oral adjunct medication comprises chlorpheniramine and hydrocodone.

### Claim 16 (depends on 1)

The method of claim 1, wherein the oral antibiotic comprises cefdinir and the oral adjunct medication comprises pseudoephedrine, methscopolamine and chlorpheniramine.

### Claim 17 (depends on 1)

The method of claim 1, wherein the oral antibiotic comprises cefdinir and the oral adjunct medication comprises chlorpheniramine and hydrocodone.

### Claim 18 (depends on 1)

The method of claim 1, wherein the oral antibiotic comprises cefdinir and the oral adjunct medication comprises dextromethorphan and guaifenesin.

### Claim 19 (depends on 1)

The method of claim 1, wherein the oral antibiotic comprises cefditoren and the oral adjunct medication comprises carbetapentane and pseudoephedrine.

### Claim 20 (depends on 1)

The method of claim 1, wherein the oral antibiotic comprises cefditoren and the oral adjunct medication comprises carbetapentane, guaifenesin, phenylephrine, and hydrocodone.

### Claim 21 (depends on 1)

The method of claim 1, wherein the oral antibiotic comprises cefditoren and the oral adjunct medication comprises benzonatate.

### Claim 22 (depends on 1)

The method of claim 1, wherein the oral antibiotic comprises cefditoren and the oral adjunct medication comprises carbetapentane, guaifenesin and phenyephrine.

### Claim 23 (depends on 1)

The method of claim 1, wherein the oral antibiotic comprises cefprozil and the oral adjunct medication comprises benzonatate.

### Claim 24 (depends on 1)

The method of claim 1, wherein the oral antibiotic comprises cefuroxime axetil and the oral adjunct medication comprises chlorpheniramine and hydrocodone.

### Claim 25 (depends on 1)

The method of claim 1, wherein the oral antibiotic comprises clarithromycin and the oral adjunct medication comprises pseudoephedrine, hydrocodone and guaifenesin.

### Claim 26

A method of providing a treatment regimen for a lower respiratory tract infection condition in a subject in need thereof, the method comprising:
(a) providing a prepackaged dosage dispenser comprising an oral antibiotic effective for treating a bacterial infection related to a lower respiratory tract infection condition and a oral adjunct medication selected from antitussives, expectorants, antihistamines, decongestants, anticholinergics, mucolytics and combinations thereof; and
(b) providing administering indicia for administering the oral antibiotic and the oral adjunct medication for treating a lower respiratory tract infection condition, the indicia being integrated with the prepackaged dosage dispenser.

### Claim 27 (depends on 26)

The method of treating bronchitis of claim 26, wherein the treatment regimen provides for improved therapeutic compliance.

### Claim 28 (depends on 26)

The method of treating bronchitis of claim 26, wherein the treatment regimen provides for reduced medication error.

### Claim 29 (depends on 26)

The method of claim 26, wherein the at least one oral antibiotic is selected from the class of antibiotics consisting of penicillins, cephalosporins and macrolides.

### Claim 30 (depends on 26)

The method of claim 26, wherein the at least one oral antibiotic is selected from the group consisting of amoxicillin, azithromycin, cefdinir, cefditoren, cefprozil, cefuroxime and clarithromycin.

### Claim 31 (depends on 26)

The method of claim 26, wherein the at least one oral adjunct medication is selected from the group consisting of benzonatate, carbetapentane, chlorpheniramine, dextromethorphan, guaifenesin, hydrocodone, methscopolamine, phenylephrine and pseudoephedrine.

### Claim 32 (depends on 26)

The method of claim 26, wherein the at least one oral adjunct medication is an decongestant.

### Claim 33 (depends on 26)

The method of claim 26, wherein the decongestant is phenylephrine, phenylpropanolamine or pseudoephedrine.

### Claim 34 (depends on 26)

The method of claim 26, wherein the at least one oral antibiotic is selected from the group consisting of amoxicillin, azithromycin, cefdinir, cefditoren, cefprozil, cefuroxime and clarithromycin; and the at least one oral adjunct medication is phenylephrine or pseudoephedrine.

### Claim 35 (depends on 26)

The method of claim 26, wherein the oral antibiotic comprises amoxicillin/clavulanate and the oral adjunct medication comprises phenylephrine and guaifenesin.

### Claim 36 (depends on 26)

The method of claim 26, wherein the oral antibiotic comprises amoxicillin/clavulanate and the oral adjunct medication comprises pseudoephedrine.

### Claim 37 (depends on 26)

The method of claim 26, wherein the oral antibiotic comprises azithromycin and the oral adjunct medication comprises pseudoephedrine, guaifenesin and dextromethorphan.

### Claim 38 (depends on 26)

The method of claim 26, wherein the oral antibiotic comprises azithromycin and the oral adjunct medication comprises chlorpheniramine and hydrocodone.

### Claim 39 (depends on 26)

The method of claim 26, wherein the oral antibiotic comprises cefdinir and the oral adjunct medication comprises pseudoephedrine, methscopolamine and chlorpheniramine.

### Claim 40 (depends on 26)

The method of claim 26, wherein the oral antibiotic comprises cefdinir and the oral adjunct medication comprises chlorpheniramine and hydrocodone.

### Claim 41 (depends on 26)

The method of claim 26, wherein the oral antibiotic comprises cefdinir and the oral adjunct medication comprises dextromethorphan and guaifenesin.

### Claim 42 (depends on 26)

The method of claim 26, wherein the oral antibiotic comprises cefditoren and the oral adjunct medication comprises carbetapentane and pseudoephedrine.

### Claim 43 (depends on 26)

The method of claim 26, wherein the oral antibiotic comprises cefditoren and the oral adjunct medication comprises carbetapentane, guaifenesin, phenylephrine, and hydrocodone.

### Claim 44 (depends on 26)

The method of claim 26, wherein the oral antibiotic comprises cefditoren and the oral adjunct medication comprises benzonatate.

### Claim 45 (depends on 26)

The method of claim 26, wherein the oral antibiotic comprises cefditoren and the oral adjunct medication comprises carbetapentane, guaifenesin and phenyephrine.

### Claim 46 (depends on 26)

The method of claim 26, wherein the oral antibiotic comprises cefprozil and the oral adjunct medication comprises benzonatate.

### Claim 47 (depends on 26)

The method of claim 26, wherein the oral antibiotic comprises cefuroxime axetil and the oral adjunct medication comprises chlorpheniramine and hydrocodone.

### Claim 48 (depends on 26)

The method of claim 26, wherein the oral antibiotic comprises clarithromycin and the oral adjunct medication comprises pseudoephedrine, hydrocodone and guaifenesin.