Oligoribonucleotides for the treatment of degenerative skin conditions by rna interference
AssigneeBeiersdorf AG
InventorsUte Breitenbach, Stefan Gallinat, Ludger Kolbe, Thomas Blatt, Helga Biergiesser, Rainer Wolber, Franz Stab, Kyra Sanger
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Abstract
The invention relates to oligoribonucleotides, which are capable of inducing breakdown of the mrna enzymes that break down connective tissue, and to pharmaceutical and cosmetic compositions, which are provided for topical application and which contain the oligoribonucleotides. The compositions are particularly suited for treating degenerative skin disorders.
Claims28
Double-stranded oligoribonucleotide or a physiologically compatible salt thereof which is capable of interfering with a RNA target sequence of a connective tissue decomposing enzyme.
Dependencies are inferred from the claim text.