Ultrasensitive amperometric saliva glucose sensor strip

An apparatus for processing a mammalian saliva sample comprising:

• a saliva sample port for receiving the saliva sample;
• and
• a filter in fluid communication with the sample port, the filter including:
• a nanofiltration material configured to remove high molecular weight contaminants from the saliva sample;
• and
• a porous absorbent material configured to absorb at least a portion of the saliva sample,
• wherein the saliva sample is filtered by the nanofiltration material and the absorbent material.

A method for determining glucose levels in a mammalian saliva sample comprising:

• receiving the saliva sample at a sample port;
• transporting at least a portion of the received saliva sample from the sample port to a measurement zone;
• combining the transported saliva sample with an enzymatic catalyst within the measurement zone;
• measuring a glucose level of the saliva sample with a minimum sensitivity of at least about 50 micromolar glucose concentration and a noise level of less than about 0.5 nA/μM/mm2.