Radiopharmaceutical administration methods, fluid delivery systems and components thereof

A vented cannula for drawing fluid from a container, the vented cannula comprising:

• a main hub comprising two opposed lateral sides and defining a fluid port and a vent;
• a fluid draw needle in connection with the fluid port and adapted to be placed within the container;
• a vent needle in connection with the vent and adapted to be placed within the container;
• and
• two resilient arms connected to the opposed lateral sides of the main hub, each of the two arms comprising a top edge and a hook member formed thereon and extending outwardly therefrom.

A method of calibrating a fluid delivery system for delivering a pharmaceutical containing a radioisotope to a patient, the method comprising:

• measuring an activity level of a first radioisotope in an ionization chamber of the fluid delivery system, the first radioisotope having an energy level less than that of the radioisotope to be delivered to the patient;
• comparing the measured activity level of the first radioisotope to an expected activity level of the first radioisotope;
• adjusting the gain of the ionization chamber to compensate for the difference, if any, between the measured activity and the expected activity of the first radioisotope;
• measuring an activity level of a second radioisotope in the ionization chamber of the fluid delivery system, the second radioisotope having an energy level similar to or greater than that of the radioisotope to be delivered to the patient;
• comparing the measured activity level of the second radioisotope to an expected activity level of the second radioisotope;
• adjusting the gain of the ionization chamber to compensate for the difference, if any, between the measured activity and the expected activity of the second radioisotope;
• and
• calculating an estimated en-or in a measured activity of a third radioisotope based on the differences, if any, between the measured activity and the expected activity of the first radioisotope and the measured activity and the expected activity of the second radioisotope.

A method of priming at least a portion of a fluid path set in a fluid delivery system, the method comprising:

• placing a tubing section of the fluid path set in fluid connection with a source of a radiopharmaceutical;
• placing a portion of the tubing section within a dose calibrator of the fluid delivery system;
• pumping a volume of the radiopharmaceutical through the tubing section;
• monitoring the dose calibrator to determine if a measured activity level is substantially equal to or above a predetermined activity level;
• and
• if the measured activity level is substantially equal to or above the predetermined activity level, then concluding that the tubing section of the fluid path set has been primed.

A fluid delivery system, comprising:

• a housing having an upper surface defining a plurality of recessed portions for accommodating one or more components of a fluid path set;
• a cover movably connected to the housing and adapted to move between a first position that exposes the upper surface and a second position that overlies the upper surface;
• and.
• a locking mechanism associated with the cover and adapted to lock the cover in the second position.

A fluid delivery system, comprising:

• a syringe comprising a body defining a discharge outlet and a plunger movably disposed within the body;
• a connector comprising a valve member and defining first, second and third ports;
• a first tubing segment connected between the discharge outlet of the syringe and the first port of the connector;
• a cannula defining a fluid port;
• a second tubing segment connected between the fluid port of the cannula and the second port of the connector;
• a third tubing segment comprising a first end connected to the third port of the connector and a second end comprising a second connector;
• and
• a per-patient tubing set comprising a first end that is adapted to be connected to the second connector on the second end of the third tubing segment and a patient end that is adapted to be connected to venous access device in a patient.