Agents which regulate, inhibit, or modulate the activity and/or expression of connective tissue growth factor (ctgf) as a unique means to both lower intraocular pressure and treat glaucomatous retinopathies/optic neuropathies
AssigneeAlcon Research, Ltd.
InventorsDebra L. Fleenor, Allan Shepard, Nasreen Jacobson, Iok-Hou Pang, Abbot F. Clark
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Abstract
The present invention provides a method for lowering intraocular pressure and providing neuroprotection to a patient in need thereof by administering a therapeutically effective amount of at least one non-nucleotide or non-protein agent that inhibits expression and/or signaling of connective tissue growth factor (CTGF).
Claims3
A composition for lowering intraocular pressure and providing neuroprotection in a patient in need thereof, said composition comprising at least one agent that inhibits the expression, signaling, or biological functions of connective tissue growth factor (CTGF) and a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.