Methods and compositions for treatment of ocular neovascularization and neural injury
AssigneeAllergan, Inc.
InventorsLarry A. Wheeler, Gerald W. DeVries
Life of this patent
Estimating the term…
Abstract
Methods and compositions for the treatment of ocular neovascularization and macular degeneration. The invention includes combining photodynamic therapy with administration of a neuroprotectant and a neovascularization inhibitor.
Claims10
A method of protecting or preventing ocular neural tissue from damage caused by laser-aided occlusion of ocular blood vessels comprising delivering a composition to a patient's ocular neural tissue, the composition comprising an amount of memantine or a salt or ester thereof, effective to protect a plurality of ocular neurons from cell death caused by a photoactive component of the PDT treatment as compared to the degree of ocular neuron cell death observed in the absence of the administration of said amount of brimonidine.
Dependencies are inferred from the claim text.