Process For the Preparation of Polynuclear Ferric Hydroxide-Saccaride Complexes
AssigneeChongqing Pharmaceutical Research Institute Co., Ltd.
InventorsJinmai Xiao, Jie Deng, Jinhua Feng, Bo Xiao
Life of this patent
Estimating the term…
Loading patent…
AssigneeChongqing Pharmaceutical Research Institute Co., Ltd.
InventorsJinmai Xiao, Jie Deng, Jinhua Feng, Bo Xiao
Estimating the term…
The invention discloses a process for preparing a polynuclear ferric hydroxide-saccharide complex, including: adding an aqueous solution of an alkaline substance drop-wise into an aqueous solution of iron salt at a temperature of 5-20° C. until pH 6-8, collecting the polynuclear ferric hydroxide from the reaction mixture by a conventional method; reacting the polynuclear ferric hydroxide with a saccharide in a solution of an alkaline substance for 10-40 hours at 106-125° C. under pH 10-12, resulting in a crude product having an isoelectric point of 4.4-5.3 and a weight average molecular weight of 20,000-100,000 Daltons, and then harvesting the polynuclear ferric hydroxide-saccharide complex from the crude product. The process can precisely control the molecular weight of the polynuclear ferric hydroxide-saccharide complex without an effect on the other characteristics of the product, for example its saccharide content or isoelectric point etc. Furthermore, it is very simple and readily applicable in industry.
A method for preparing a ferric-saccharide complex, comprising:
(canceled)
A method for preparing a polynuclear ferric hydroxide-saccharide complex, comprising:
(canceled)
Dependencies are inferred from the claim text.