Use Of Diosmetin Compounds In The Treatment And Prevention Of Thrombotic Pathologies

A method of treating a living animal body, including a human, afflicted with thrombotic pathologies comprising the step of administering to the living animal body, including a human, an amount of a diosmetin compound of formula (I)

• wherein:
• R1 represents a hydrogen atom or a propyl or allyl radical;
• R2 represents a hydrogen atom or a propyl, allyl, 2,3-dihydroxypropyl, (2,2-dimethyl-1,3-dioxol-4-yl)methyl or 3-acetyloxy-2-hydroxypropyl radical;
• R3 represents a hydrogen atom or a propyl or allyl radical;
• R4 represents a hydrogen atom or a methyl, propyl, allyl, 2,3-dihydroxypropyl or (2,2-dimethyl-1,3-dioxol-4-yl)methyl radical or a radical of formula —COR′4 wherein R′4 represents a linear or branched (C1-C5)alkyl radical or a phenyl radical;
• R5 represents a hydrogen atom or a propyl or allyl radical, and
• R6 represents a hydrogen atom or a methyl, propyl, allyl, 2,3-dihydroxypropyl or (2,2-dimethyl-1,3-dioxol-4-yl)methyl radical, a radical of formula —COR′6 (wherein R′6 represents a linear or branched (C1-C5)alkyl radical or a phenyl radical) or a radical of formula (I′)
• provided that:
• at least one of the groups R1, R2, R3, R4, R5 and R6 is other than a hydrogen atom and,
• if R1, R2 and R3 each simultaneously represent a hydrogen atom, then R4 also represents a hydrogen atom,
• its diastereoisomers and enantiomers, and
• addition salts thereof with a pharmaceutically acceptable acid or base,
• which is effective for the prevention and/or treatment of thrombotic pathologies.