Derivatives of 4,5-diarylpyrrole, preparation method thereof and use of same in therapeutics

A compound having the formula (I):

• in which:
• X represents a group
• R1 represents a hydrogen atom or a (C1-C4)alkyl group;
• R2 represents:
• a (C1-C12)alkyl which is unsubstituted or substituted one or more times with substituents chosen independently from a halogen atom, a hydroxyl, a (C1-C4)alkoxy, a (C1-C4)alkylthio, a phenoxy, a trifluoromethoxy radical, a difluoromethoxy radical, a difluoromethylthio radical and a trifluoromethylthio radical;
• a nonaromatic carbocyclic (C3-C12) radical which is unsubstituted or substituted one or more times with substituents chosen independently from a (C1-C4)alkyl, a (C1-C4)alkoxy, a (C1-C4)alkylthio, a fluorine atom, a hydroxyl, a trifluoromethyl radical, a difluoromethyl radical, a trifluoromethoxy radical, a difluoromethoxy radical, a trifluoromethylthio radical and a difluoromethylthio radical;
• a methyl substituted with a nonaromatic carbocyclic (C3-C12) radical which is unsubstituted or substituted one or more times with substituents chosen independently from a (C1-C4)alkyl, a (C1-C4)alkoxy, a (C1-C4)alkylthio, a fluorine atom, a hydroxyl, a trifluoromethyl radical, a difluoromethyl radical, a trifluoromethoxy radical, a difluoromethoxy radical, a trifluoromethylthio radical and a difluoromethylthio radical;
• a phenyl, benzyl, benzhydryl or benzhydrylmethyl radical, in which each phenyl group is unsubstituted or substituted one or more times with substituents chosen independently from a halogen atom, a hydroxyl, a (C1-C4)alkyl, a (C1-C4)alkoxy, a methylenedioxy, a cyano, a nitro, a trifluoromethyl, a difluoromethyl, a difluoromethoxy, a trifluoromethoxy, a trifluoromethylthio, a difluoromethylthio, an S(O)nAlk group, an OS(O)nAlk group and a (C1-C4) alkylcarbonyl group;
• a phenyl radical substituted with a heterocyclic radical chosen from pyrrolyl, imidazolyl, pyridyl or pyrazolyl, said heterocyclic radical being unsubstituted or substituted one or more times with one or more substituents chosen independently from a halogen atom or a (C1-C4)alkyl group;
• a phenyl radical substituted with a phenyl or a phenoxy, in which each phenyl group is unsubstituted or substituted one or more times with substituents chosen independently from a halogen atom, a hydroxyl, a (C1-C4)alkyl, a (C1-C4)alkoxy, a methylenedioxy, a cyano, a nitro, a trifluoromethyl, a difluoromethyl, a difluoromethoxy, a trifluoromethoxy, a trifluoromethylthio, a difluoromethylthio, an S(O)nAlk group, an OS(O)nAlk group and a (C1-C4)alkylcarbonyl group;
• a 1,2,3,4-tetrahydronaphthalen-2-yl which is unsubstituted or substituted one or more times with a (C1-C4)alkyl or a trifluoromethyl;
• a pyrrolyl, imidazolyl, pyridyl, pyrazolyl, furyl, thienyl, oxazolyl or thiazolyl radical, said radicals being unsubstituted or substituted with one or more substituents chosen independently from a halogen atom, a (C1-C4)alkyl group or a trifluoromethyl group;
• an indol-2-yl or an N-methylindol-2-yl;
• R3 represents a (C1-C5)alkyl or a (C3-C7)cycloalkyl;
• R4 represents a phenyl which is unsubstituted or substituted one or more times with substituents chosen independently from a halogen atom, a (C1-C4)alkyl, a (C1-C4)alkoxy, a cyano, a difluoromethyl radical, a trifluoromethyl radical, a difluoromethoxy radical, a trifluoromethoxy radical, an S(O)nAlk group or an OS(O)nAlk group;
• R5 represents a phenyl which is unsubstituted or substituted one or more times with substituents chosen independently from a halogen atom, a (C1-C4)alkyl, a (C1-C4)alkoxy, a cyano, a difluoromethyl radical, a trifluoromethyl radical, a difluoromethoxy radical, a trifluoromethoxy radical, an S(O)nAlk group or an OS(O)nAlk group;
• R6 represents a hydrogen atom or a (C1-C4)alkyl;
• n represents 0, 1 or 2;
• and
• Alk represents a (C1-C4)alkyl;
• or
• a salt or a hydrate or a solvate thereof.