Intermediates and Methods for Forming Passivated Surfaces on Oxide Layers and Articles Produced Thereby

A compound of the formula (I), formula (II), or formula (III) below:

• wherein:
• X is O, N or a methylene group;
• R3 is polyethylene glycol, a substituted polyethylene glycol, a hydrocarbon, a substituted hydrocarbon, a fluorocarbon or a substituted fluorocarbon;
• and
• R4 is N(R2)4, or M, wherein M is Li, Na, K or Cs and wherein R2 is an alkyl group.

A compound of the formula:

• Y(L-Pol)m
• wherein Y is a transition metal, magnesium or aluminum,
• L is oxygen, sulfur, selenium or an amine,
• each “Pol” group independently represents a polyethylene glycol, a substituted polyethylene glycol, a hydrocarbon, a substituted hydrocarbon, a fluorocarbon or a substituted fluorocarbon, and
• m is an integer.

A method comprising:

• reacting a first compound of the formula:
• Y(OR6)m
• with one or more second compounds of the formula:
• Pol-LH
• to form a metal ester compound of the formula
• Y(L-Pol)m
• wherein:
• Y is a transition metal, magnesium or aluminum,
• R6 is a C1-C5 hydrocarbon,
• L is oxygen, sulfur, selenium or an amine,
• each “Pol” group independently represents a polyethylene glycol, a substituted polyethylene glycol, a hydrocarbon, a substituted hydrocarbon, a fluorocarbon or a substituted fluorocarbon, and
• m is an integer.

A solid support comprising:

• an oxide layer comprising an oxide of silicon, aluminum, germanium, gallium, indium, magnesium or tin;
• and
• moieties on a surface of the oxide layer, the moieties having a structure as set forth in formula (I) or formula (II) below:
• wherein:
• X is O, N or a methylene group
• Y is a transition metal, magnesium or aluminum,
• L is oxygen, sulfur, selenium or an amine or L is a metal complexing agent,
• each “Pol” group independently represents a polyethylene glycol, a substituted polyethylene glycol, a hydrocarbon, a substituted hydrocarbon, a fluorocarbon or a substituted fluorocarbon,
• R3 is polyethylene glycol, a substituted polyethylene glycol, a hydrocarbon, a substituted hydrocarbon, a fluorocarbon or a substituted fluorocarbon, and
• m is an integer;
• and
• wherein the oxygen atoms are bonded to the same or to different silicon, aluminum, germanium, gallium, indium, magnesium or tin atoms in the oxide layer.

A solid support comprising:

• an oxide layer comprising an oxide of silicon, aluminum, germanium, gallium, indium, magnesium or tin;
• atoms of a metal selected from the group consisting of a transition metal, magnesium and aluminum bonded to the oxide layer;
• and
• a passivating reagent comprising a passivating moiety selected from the group consisting of a substituted polyethylene glycol, an unsubstituted polyethylene glycol, a hydrocarbon, a substituted hydrocarbon, a fluorocarbon and a substituted fluorocarbon;
• wherein the passivating reagent is covalently bonded to or forms a complex with one or more atoms of the metal at a plurality of locations.