Nucleic acids and proteins of insect Or83b odorant receptor genes and uses thereof
AssigneeSentiSearch, Inc.
InventorsKevin J. Lee, Thuy-Ai T. Nguyen, Brian Kloss
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AssigneeSentiSearch, Inc.
InventorsKevin J. Lee, Thuy-Ai T. Nguyen, Brian Kloss
Estimating the term…
The present invention relates to insect odorant receptor genes and methods for identifying odorant receptor genes. The invention provides nucleotide sequences of insect odorant receptor genes Or83b, amino acid sequences of their encoded proteins (including peptides or polypeptides), and related products and methods. The nucleic acids of the invention may be operatively linked to promoter sequences and transformed into host cells. Methods of production of an Or83b odorant receptor protein (e.g., by recombinant means), and derivatives and analogs thereof, are provided. Antibodies to an Or83b odorant receptor protein, and derivatives and analogs thereof, are provided. Methods for identifying molecules that bind or modulate the activity of these Or83b odorant receptor genes are provided. Molecules found to bind or modulate the activity of Or83b genes may be formulated into pest control agents by providing a carrier. In a preferred embodiment, molecules that bind or modulate the activity of an Or83b gene from one species but not others is desired. Methods to modify the insect behavior by modifying an insect Or83b odorant are also provided.
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An isolated nucleic acid molecule comprising a nucleotide sequence encoding a polypeptide with an amino acid sequence having at least 80 identity of at least 20 continuous amino acids of the amino acid sequence of SEQ ID NO:11, with the proviso that said amino acid sequence is not found in SEQ ID NO:10.
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Dependencies are inferred from the claim text.