Methods and compositions for modulating apoptotic pathways
AssigneeThe Research Foundation of State University of New York
InventorUte Moll
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Abstract
The present invention relates to methods, compositions and systems for modulating apoptotic pathways. In particular, the present invention relates to methods, compositions and systems for inducing apoptosis in cancer cells. The present invention further relates to methods, compositions and systems for identifying drugs that modulate apoptotic pathways.
Claims10
A nucleic acid comprising an exogenous p53 gene operably linked to a gene encoding a mitochondrial targeting protein.
An adenovirus gene transfer system comprising an adenoviral vector comprising an exogenous p53 gene operably linked to a gene encoding a mitochondrial targeting protein.
Dependencies are inferred from the claim text.