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US 2008/0176306 A1Published application
Methods for Sterilizing Biological Materials
OwnerMartin J. MacPhee, Randall S. Kent +2inventors
InventorsMartin J. MacPhee, Randall S. Kent, Edward A. Horton, Dawson Beall
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Abstract
Methods are disclosed for sterilizing biological products to reduce the level of active biological contaminants such as viruses, bacteria, yeasts, molds, mycoplasmas and parasites.
Claims17
1-26. (canceled)
A method for reducing the level of active biological contaminants or pathogens in bone, comprising
- contacting the bone with a composition comprising DMSO, trehalose and mannitol;
- and
- irradiating the bone-containing composition with gamma radiation,
- wherein the total dose of gamma radiation is at least about 12 kGy.
1 more element
Dependencies are inferred from the claim text.