Gene Coding for Glucose-6-Phosphate-Dehydrogenase Proteins
OwnerOskar Zelder, Markus Pompejus +4inventors
InventorsOskar Zelder, Markus Pompejus, Hartwig Schroder, Burkhard Kroger, Corinna Klopprogge, Gregor Haberhauer
Life of this patent
Estimating the term…
Abstract
The present invention relates to isolated nucleic acid molecules encoding mutants of glucose-6-phosphate dehydrogenase, and vectors and hosts cells including such nucleic acid molecules. These nucleic acid molecules are involved in the biosynthesis of a fine chemical, e.g., an amino acid such as lysine. The present invention also relates to methods of producing and modulating the production of fine chemicals, e.g., lysine, by culturing recombinant microorganisms containing these nucleic acid molecules under conditions such that the fine chemical is produced.
Claims8
An isolated nucleic acid molecule, coding for a polypeptide having the amino acid sequence referred to in each case in Table 1/column 2, wherein the nucleic acid molecule in the amino acid position indicated in table 1/column 4 encodes a proteinogenic amino acid different from the particular amino acid indicated in Table 1/column 5 in the same row.
Dependencies are inferred from the claim text.