Materials and Methods for Efficient and Accurate Detection of Analytes
AssigneeUniversity of Florida Research Foundation, Inc.
InventorsGregory Schultz, John I. Azeke, Daniel J. Gibson, Olajompo Busola Moloye, Priscilla Lorraine Phillips, Weihong Tan, Christopher D. Batich
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Abstract
The present invention provides diagnostic methods and devices that can be used to assay a medium, such as tissue in vivo or a sample in vitro (e.g. biological sample or environmental sample), in order to determine the presence, quantity, and/or concentration ratio of one or more target analytes.
Claims36
A device for simultaneously determining relative concentrations of multiple target molecules in a medium.
A method for detecting an analyte in a sample wherein said method is selected from the group consisting of:
- a) a FRET assay;
- b) an assay utilizing a thin film of substrate wherein digestion of the substrate by an analyte is visualized;
- and
- c) a fluorescence-based diagnostic strip.
A method for evaluating the status of the healing process of a wound wherein said method comprises contacting a tissue or fluid sample obtained from the wound with a peptide that is cleaved by one or more proteases associated with wound healing, wherein if cleavage of the peptide occurs due to a protease in the sample, a detectable event occurs in less than 30 minutes from the time of contact.
An assay device comprising a thin film of a substrate for an analyte.
As assay strip substantially as depicted in FIG. 3.
Dependencies are inferred from the claim text.