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US 2008/0176244 A1Published application
Usage of exocyst complex component or sec3 or its homolog in delivery of exogenous molecules in transit
OwnerShen Quan PANinventor
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OwnerShen Quan PANinventor
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The invention relates to the usage of Exocyst complex component or Sec3 or its homolog as a molecular marker for monitoring an exogenous molecule like nucleic acid in transit and optimizing the delivery of the exogenous molecule to a cell. Delivery of the molecule is monitored by detecting expression of an Exocyst complex component or Sec3 or its homolog in said cell, wherein the expression of the Exocyst complex component or Sec 3 or its homolog indicates that the cell is competent to receive the exogenous molecule. The invention may be used (a) to determine the efficiency of delivery; (b) to control the copy number of DNA delivery; (c) to identify the cells transformed with an exogenous DNA; (d) to identify molecular markers associated with transformation competency of a cell; (e) identifying, characterizing and producing cells competent to receive exogenous nucleic acid.
A process for identifying a cell that is competent for receiving an exogenous nucleic acid, the process comprising detecting the expression of an Exocyst complex component or Sec3 or a Sec3 homolog;
A kit for monitoring competency of cells for uptake of an exogenous nucleic acid comprising:
A method for producing cells competent to receive an exogenous molecule comprising
A process for introducing an exogenous molecule into a cell, the process comprising
Dependencies are inferred from the claim text.