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US 2008/0175917 A1Published application
Microparticles containing a H+,K+-ATP-ase inhibitor
OwnerHakan Glad, Malin Soderbominventors
Life of this patent
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Abstract
A method for the preparation of homogenous microparticles containing a H+, K+-ATP-ase inhibitor using a fluid-bed granulation technique. The microparticles that have a desired size distribution are selected. At least 80% of the microparticle based on its dry weight content is the acid labile H+, K+-ATP-ase inhibitor.
Claims10
1-16. (canceled)
A homogeneous microparticle comprising an acid labile H+,K+-ATPase inhibitor, wherein the microparticle comprises:
- an acid labile H+,K+-ATPase inhibitor, an alkaline salt thereof, a single enantiomer of the H+,K+-ATPase inhibitor, or an alkaline salt of the single enantiomer, which comprises at least 80% by weight of the microparticle based on its dry content;
- and
- (ii) a water-soluble or water-insoluble polymer, which comprises at least 5% by weight of the microparticle based on its dry content.
25-26. (canceled)
Dependencies are inferred from the claim text.