Pyridoxal-5-Phosphate And Stent For The Treatment And Prevention Of Atherosclerosis And Restenosis
AssigneeMeidcure International Inc.
InventorMarjorie Zettler
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Abstract
The present invention provides method of treating and preventing vascular inflammation, atherosclerosis, restenosis, plaque destabilization and bypass graft failure comprising the administration of a therapeutically effective amount of pyridoxal-5′-phosphate or a pharmaceutically acceptable salt thereof. The present invention further provides an intravascular stent for use with a narrowed artery having at least one surface reversibly bound with pyridoxal-5′-phosphate or a pharmaceutically acceptable salt thereof.
Claims23
A method of treating a condition selected from the group consisting of vascular inflammation, atherosclerosis, restenosis, plaque destabilization, and bypass graft failure, comprising administering to a patient in need thereof, a therapeutically effective amount of pyridoxal-5′-phosphate or pharmaceutically acceptable salt thereof.
A method of treating atherosclerosis in a patient suffering thereof comprising administering to the patient a therapeutically effective amount of pyridoxal-5′-phosphate or a pharmaceutically acceptable salt thereof, prior to the patient undergoing a percutaneous coronary intervention.
17-20. (canceled)
An intravascular stent for use with a narrowed artery wherein said stent has at least one surface reversibly bound with pyridoxal-5′-phosphate or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.