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US 2008/0175864 A1Published application
Treating hepatitis C virus infection
AssigneeBoard of Regents, The University of Texas System
InventorsJin Ye, Fang Sun, Hua Huang, Michael J. Gale
Life of this patent
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Abstract
Methods and compositions are provided to inhibit release of HCV from an HCV-infected cell by contacting the cell with a VLDL assembly inhibitor, and detecting a resultant inhibition of HVC release from the cell. The methods can be used to decrease serum viremia of an HCV-infected person.
Claims15
A method of inhibiting release of HCV from an HCV-infected cell, the method comprising:
- a) contacting the cell with a VLDL assembly inhibitor;
- and
- b) detecting a resultant inhibition of HCV release from the cell.
A method of decreasing serum viremia of an HCV-infected person, the method comprising:
- a) administering to the person a VLDL assembly inhibitor;
- and
- b) detecting a resultant decrease in serum viremia in the person.
A kit for decreasing serum viremia for an HVC-infected person, the kit comprising:
- a) a plurality of MTP-inhibitor dosage forms;
- and
- b) a plurality of ribavirin dosage forms.
Dependencies are inferred from the claim text.