Methods for treating angiogenesis related disorders
AssigneeThe Scripps Research Institute
InventorsPeter Brooks, David A. Cheresh
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Abstract
The present invention describes methods for inhibition angiogenesis in tissues using vitronectin αvβ3 antagonists, and particularly for inhibiting angiogenesis in inflamed tissues and in tumor tissues and metastases using therapeutic compositions containing αvβ3 antagonists.
Claims34
1-16. (canceled)
A method of treating neovascular glaucoma in a patient in need thereof comprising administering to said patient a therapeutically effective amount of an antibody immunospecific for αvβ3 or an antigen binding fragment thereof.
A method of treating macular degeneration in a patient in need thereof comprising administering to said patient a therapeutically effective amount of an antibody immunospecific for αvβ3 or an antigen binding fragment thereof.
A method of inhibiting capillary proliferation in atherosclerotic plaques in a patient in need thereof comprising administering to said patient a therapeutically effective amount of an antibody immunospecific for αvβ3 or an antigen binding fragment thereof.
Dependencies are inferred from the claim text.