Method for inducing neural differentiation
AssigneeHenrich CHENG
InventorsHenrich CHENG, Shun-Fen TZENG
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Abstract
A method for inducing neural differentiation includes treating a bone marrow stem cell with a neurotrophic factor and/or dibutyryl cAMP (dbcAMP), wherein the neurotrophic factor includes or is glial cell line-derived neurotrophic factor (GDNF) or pituitary adenylate cyclase-activating polypeptide (PACAP).
Claims13
A method for treating neural injury or improving the recovery of spinal injury, the method comprising providing sieve-sized stem cells cultured with at least one of dibutyryl cAMP (dbcAMP) and a neurotrophic factor or a combination thereof, and transplanting to the neural or spinal injury the sieve-sized stem cells with the dbcAMP, the neurotrophic factor or a combination thereof.
A method for preparing a bone marrow stem cell for induction of neural differentiation, the method comprising treating a size-sieved human bone marrow stem cell with pituitary adenylate cyclase-activating polypeptide (PACAP).
Dependencies are inferred from the claim text.