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US 2008/0175798 A1Published application
Peptide-based hair protectants
OwnerWilliam A. Beck, John P. O'Brien +1inventors
InventorsWILLIAM A. BECK, John P. O'Brien, Hong Wang
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Abstract
Peptide-based hair protectants, formed by coupling at least one hair-binding peptide with at least one sunscreen agent, are described. The hair-binding peptide portion of the peptide-based hair protectant binds to hair with high affinity, thus keeping the sunscreen agent attached to the hair for long lasting protection. Hair care compositions comprising the peptide-based hair protectants are also described.
Claims23
A peptide-based hair protectant having the general structure:
- (HBPm)n-(SCA)y,
- or
- [(HBP)p-Sq]n-(SCA)y
- wherein
- a) HBP is a hair-binding peptide;
- b) SCA is a sunscreen agent;
- c) m ranges from 1 to about 100;
- d) n ranges from 1 to about 100;
- e) y ranges from 1 to about 100;
- f) S is a spacer;
- g) p ranges from 1 to 10;
- and
- h) q ranges from 1 to about 100.
10 more elements
A method for forming a protective layer on hair comprising the steps of:
- (a) providing a hair care composition comprising a peptide-based hair protectant selected from the group consisting of:
- (HBPm)n-(SCA)y;
- and i)
- [(HBP)p-Sq]n-(SCA)y ii)
- wherein
- 1) HBP is a hair-binding peptide;
- 2) SCA is a sunscreen agent;
- 3) n ranges from 1 to about 100;
- 4) S is a spacer;
- 5) m ranges from 1 to about 100;
- 6) p ranges from 1 to about 10;
- 7) q ranges from 1 to about 100;
- and
- 8) y ranges from 1 to about 100;
- and wherein the hair-binding peptide is selected by a method comprising the steps of:
- (A) providing a combinatorial library of DNA associated peptides;
- (B) contacting the library of (A) with a hair sample to form a reaction mixture comprising DNA associated peptide-hair complexes;
- (C) isolating the DNA associated peptide-hair complexes of (B);
- (D) amplifying the DNA encoding the peptide portion of the DNA associated peptide-hair complexes of (C);
- and
- (E) sequencing the amplified DNA of (D) encoding a hair-binding peptide, wherein the hair-binding peptide is identified;
- and
- (b) applying the hair care composition of (a) to hair and allowing the formation of said protective layer.
20 more elements
Dependencies are inferred from the claim text.