Low-Profile Vascular Closure Systems and Methods of Using Same

A method for closing a wall opening of a vessel of a body, the method comprising the steps of:

• providing a guiding system comprising at least two elongate stabilization wire guides and a retention foot disposed at a distal portion of each stabilization wire guide, each retention foot being selectively expandable laterally from the respective stabilization wire guide in at least one direction, the guiding system including a deployed configuration wherein the retention feet are expanded, and an undeployed configuration wherein the retention feet are unexpanded;
• providing a closure system including an elongate center tube having an elongate stapler slidably disposed there within, the center tube being coupled to at least two opposing side tubes for riding along the stabilization wire guides, respectively;
• delivering the guiding system through the wall opening into the vessel in the undeployed configuration;
• transforming the guiding system into the deployed configuration such that the retention feet are expanded within the vessel;
• advancing the closure system along the guiding system to a position proximal to the wall opening;
• and
• activating the stapler to close the opening.