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AssigneeRoche Diagnostics Operations, Inc.
InventorsBernhard Schaffar, Herbert Kroneis, Taghi Noormofidi, Gernot Florian, Wolf-Dietrich Steinbock
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In a method for calibrating a biosensor for the amperometric determination of creatinine in biological liquids, consisting of one electrode system each for measuring the concentrations of creatinine and creatine, with at least two calibration solutions being used, the electrode system for measuring the creatinine concentration is calibrated with a creatinine solution which, prior to the calibration measurement, was mixed in the form of an acidic solution with an alkaline buffer solution, and the electrode system for measuring the creatine concentration is calibrated with a solution in which creatinine and creatine are at a thermodynamic equilibrium.
A method for calibrating a biosensor for the amperometric determination of creatinine in biological liquids, wherein the biosensor has one electrode system each for measuring the concentrations of creatinine and creatine, the method comprising:
A method for calibrating a biosensor for the amperometric determination of creatinine in biological liquids, wherein the biosensor has one electrode system each for measuring the concentrations of creatinine and creatine, the method comprising providing a creatinine calibration solution and a creatine calibration solution for calibrating the electrodes, wherein the creatinine solution is prepared by mixing an acidic creatinine solution with an alkaline buffer solution, and the creatine calibration solution comprises a solution in which creatinine and creatine are at a thermodynamic equilibrium.
Dependencies are inferred from the claim text.