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AssigneeOsteologlx A/S
InventorsChristian Hansen, Henrik Nilsson, Stephan Christgau, Henry G. Bone
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A method for the treatment and/or prophylaxis of an ostenonecrotic bone disease in a mammal in need thereof, such as, e.g., idiopathic or secondary osteonecrosis, avascular bone necrosis, glucocorticoid induced bone ischemia/osteonecrosis, Legg-Calve-Perthes disease and femoral head necrosis, the method comprising administering an effective dose of a strontium-containing compound (a) to the mammal. A method for the treatment and/or prophylaxis of an osteonecrotic bone disease, such as, e.g., idiopathic or secondary osteonecrosis, avascular bone necrosis, glucocorticoid induced bone ischemia/osteonecrosis and femoral head necrosis, in a mammal who is to be or is treated with a therapeutic agent (b) known to or suspected of inducing apoptosis and/or necrosis of bone cells, the method comprising administering a strontium-containing compound (a) in combination with (b).
A method for the treatment and/or prophylaxis of an osteonecrotic bone disease in a mammal in need thereof, the method comprising administering an effective dose of a strontium-containing compound to the mammal.
A method for the treatment and/or prophylaxis of an osteonecrotic bone disease, in a mammal who is to be or is treated with a therapeutic agent known to or suspected of inducing apoptosis and/or necrosis of bone cells, the method comprising administering a strontium-containing compound in combination with the therapeutic agent.
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A pharmaceutical composition comprising a strontium-containing compound, and a therapeutic agent that is known to or suspected of inducing apoptosis and/or necrosis of bone cells leading to an osteonecrotic bone condition.
A kit comprising two or more components, the first component comprising a strontium-containing compound and the second component comprising a therapeutic agent that is known to or suspected of inducing apoptosis and/or necrosis of bone cells leading to an osteonecrotic bone condition.
Dependencies are inferred from the claim text.