Separating agent for optical isomers, method of production thereof, and separation column for optical isomers
OwnerYoshio Okamoto, Chiyo Yamamoto +1inventors
InventorsYoshio Okamoto, Chiyo Yamamoto, Chankvetadze Bezhan
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Abstract
The present invention provides a separating agent for optical isomers having a porous monolithic inorganic type carrier and polysaccharide or a derivative thereof supported on the monolithic inorganic type carrier, and a separation column for optical isomers in which the separating agent for optical isomers is held in a column tube. According to the invention, the separating agent for optical isomers and the separation column for optical isomers which have high asymmetry recognition ability and can be used particularly at a high flow rate when used for the separation of optical isomers is provided.
Claims5
A method of producing a separating agent for optical isomers which is used for separation of optical isomers in a sample and comprises:
- an monolithic inorganic type carrier that is porous;
- and at least one of polysaccharide and a polysaccharide derivative supported on the monolithic inorganic type carrier, the method comprising the steps of:
- injecting a solution of polysaccharides comprising the at least one of the polysaccharide and the polysaccharide derivative and a solvent into the monolithic inorganic type carrier under pressure from 50 to 400 bar to provide a filled carrier;
- and
- subjecting the filled carrier to at least one of distilling off the solvent from the monolithic inorganic type carrier filled with the solution and replacing the solvent with another solvent therein.
Dependencies are inferred from the claim text.